Habitual Snoring in Pediatric Thalassemia Disease; Prevalence, Quality of Life and Risk Factors
Issued Date
2023-01-01
Resource Type
eISSN
22288082
Scopus ID
2-s2.0-85168819777
Journal Title
Siriraj Medical Journal
Volume
75
Issue
8
Start Page
546
End Page
554
Rights Holder(s)
SCOPUS
Bibliographic Citation
Siriraj Medical Journal Vol.75 No.8 (2023) , 546-554
Suggested Citation
Satdhabudha A., Parnthong C., Surapolchai P., Pusongchai T., Satayasai W., Buaboonnam J., Sinlapamongkolkul P. Habitual Snoring in Pediatric Thalassemia Disease; Prevalence, Quality of Life and Risk Factors. Siriraj Medical Journal Vol.75 No.8 (2023) , 546-554. 554. doi:10.33192/smj.v75i8.263395 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/89296
Title
Habitual Snoring in Pediatric Thalassemia Disease; Prevalence, Quality of Life and Risk Factors
Author's Affiliation
Other Contributor(s)
Abstract
Objective: To compare the prevalence of HS and quality of life in non-transfusion dependent thalassemia (NTDT) and Transfusion dependent thalassemia (TDT) patients and to identify risk factors associated with HS in pediatric thalassemia. Materials and Methods: We conducted a cross-sectional study of pediatric thalassemic patients aged from 6 months - 18 years between January 2020 and October 2020, at Thammasat University Hospital, Thailand. Results: There were 141 thalassemia patients (35 TDT and 106 NTDT), aged 7 months-18 years, 73 (51.8%) were male. Sixty-eight patients (48.2%) reported snoring; 28 patients (19.9%) had HS; the remaining 40 patients (28.4%) had simple snoring. The prevalence of HS was not significantly different between TDT and NTDT group (6 (17.1%) VS 22 (20.8%); P= 0.527). Quality of life assessed by OSA-18 score was not significant difference between TDT and NTDT groups (51.3 ± 18.8 VS 45.7 ± 11.4; P=0.141). The associating risk factors for the development of HS after multivariate logistic analysis were nasal congestion, and male gender, with an adjusted OR of 5.3 and 3.0, respectively. Conclusion: Prevalence of HS was increased in children with thalassemia. Factors such as nasal congestion and male gender were strongly associated with HS in this population. The quality of life assessment using the OSA-18 questionnaire indicated that thalassemia children generally exhibited a good quality of life. Additionally, our study observed relatively low serum ferritin levels in comparison to previous studies. The standard care provided for TDT patients, includes regular blood transfusion and effective iron chelation, may contribute to slowing down the degree of nasopharyngeal narrowing in thalassemia patients.