Risk for Prison-to-Community Tuberculosis Transmission, Thailand, 2017-2020
Issued Date
2023-03-01
Resource Type
ISSN
10806040
eISSN
10806059
Scopus ID
2-s2.0-85148828228
Pubmed ID
36823074
Journal Title
Emerging Infectious Diseases
Volume
29
Issue
3
Start Page
477
End Page
483
Rights Holder(s)
SCOPUS
Bibliographic Citation
Emerging Infectious Diseases Vol.29 No.3 (2023) , 477-483
Suggested Citation
Miyahara R., Piboonsiri P., Chiyasirinroje B., Imsanguan W., Nedsuwan S., Yanai H., Tokunaga K., Palittapongarnpim P., Murray M., Mahasirimongkol S. Risk for Prison-to-Community Tuberculosis Transmission, Thailand, 2017-2020. Emerging Infectious Diseases Vol.29 No.3 (2023) , 477-483. 483. doi:10.3201/eid2903.221023 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/82669
Title
Risk for Prison-to-Community Tuberculosis Transmission, Thailand, 2017-2020
Author's Affiliation
Fukujuji Hospital
Harvard T.H. Chan School of Public Health
National Institute of Infectious Diseases
The University of Tokyo
National Center for Global Health and Medicine
Thailand Ministry of Public Health
Mahidol University
Harvard Medical School
Chiangrai PrachChanukroh Hospital
National Center Biobank Network
TB/HIV Research Foundation
Harvard T.H. Chan School of Public Health
National Institute of Infectious Diseases
The University of Tokyo
National Center for Global Health and Medicine
Thailand Ministry of Public Health
Mahidol University
Harvard Medical School
Chiangrai PrachChanukroh Hospital
National Center Biobank Network
TB/HIV Research Foundation
Other Contributor(s)
Abstract
To determine contributions of previously incarcerated persons to tuberculosis (TB) transmission in the community, we performed a healthcare facility-based cohort study of TB patients in Thailand during 2017-2020. We used whole-genome sequencing of Mycobacterium tuberculosis isolates from patients to identify genotypic clusters and assess the association between previous incarceration and TB transmission in the community. We identified 4 large genotype clusters (>10 TB patients/ cluster); 28% (14/50) of the patients in those clusters were formerly incarcerated. Formerly incarcerated TB patients were more likely than nonincarcerated patients to be included in large clusters. TB patients within the large genotype clusters were geographically dispersed throughout Chiang Rai Province. Community TB transmission in the community was associated with the presence of formerly incarcerated individuals in Thailand. To reduce the risk for prison-to-community transmission, we recommend TB screening at the time of entry and exit from prisons and follow-up screening in the community.