Platinum/carbon dots nanocomposites from palm bunch hydrothermal synthesis as highly efficient peroxidase mimics for ultra-low H<inf>2</inf>O<inf>2</inf> sensing platform through dual mode of colorimetric and fluorescent detection
Issued Date
2022-10-16
Resource Type
ISSN
00032670
eISSN
18734324
Scopus ID
2-s2.0-85138162548
Pubmed ID
36192059
Journal Title
Analytica Chimica Acta
Volume
1230
Rights Holder(s)
SCOPUS
Bibliographic Citation
Analytica Chimica Acta Vol.1230 (2022)
Suggested Citation
Saengsrichan A., Khemthong P., Wanmolee W., Youngjan S., Phanthasri J., Arjfuk P., Pongchaikul P., Ratchahat S., Posoknistakul P., Laosiripojana N., Wu K.C.W., Sakdaronnarong C. Platinum/carbon dots nanocomposites from palm bunch hydrothermal synthesis as highly efficient peroxidase mimics for ultra-low H<inf>2</inf>O<inf>2</inf> sensing platform through dual mode of colorimetric and fluorescent detection. Analytica Chimica Acta Vol.1230 (2022). doi:10.1016/j.aca.2022.340368 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/83579
Title
Platinum/carbon dots nanocomposites from palm bunch hydrothermal synthesis as highly efficient peroxidase mimics for ultra-low H<inf>2</inf>O<inf>2</inf> sensing platform through dual mode of colorimetric and fluorescent detection
Other Contributor(s)
Abstract
Detection of hydrogen peroxide and glucose in nanomolar level is crucial for point-of-care medical diagnosis. It has been reported that human's central nervous system diseases such as Alzheimer's disease, Parkinson's disease, and even amyotrophic lateral sclerosis, are presumably caused H2O2 or reactive radical species (ROS). Sensing of H2O2 released from human biofluids, tissues, organ from metabolism disorder at ultra-low concentration assists for early identification of severe diabetis mellitus related to glucose, and heart attack, as well as stroke related to cholesterol. In this work, carbon dots (CDs) having an average diameter at 6.99 nm with highly photoluminescence performance were successfully synthesized from palm empty fruit bunch (EFB) using green and environmentally friendly process via hydrothermal condition. CDs acted well on peroxidase-like activity for H2O2 detection at room temperature, however their sensitivity on ultra-low H2O2 concentration needed to be improved. To enhance their reactivity on H2O2 nanozyme activity at room temperature, synthesis of hybrid metal nanoparticles (AgNPs and PtNPs) on CDs surface was established. The findings exhibited that CDs/PtNPs was the most suitable nanozyme achieving highly efficient peroxidase mimic for dual mode of colorimetric and fluorescent H2O2 sensing platform at very low limit of detection of 0.01 mM (10 nM) H2O2.