Pulmonary Hypertension in Mitral Valve Disease-Rheumatic Mitral Stenosis versus Organic Mitral Regurgitation: The Doppler-Echocardiographic Study Revisited
Issued Date
2022-12-01
Resource Type
ISSN
01252208
Scopus ID
2-s2.0-85144427317
Journal Title
Journal of the Medical Association of Thailand
Volume
105
Issue
12
Start Page
1208
End Page
1215
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand Vol.105 No.12 (2022) , 1208-1215
Suggested Citation
Ratanasit N., Karaketklang K., Rasmeehirun P., Chanwanitkulchai R. Pulmonary Hypertension in Mitral Valve Disease-Rheumatic Mitral Stenosis versus Organic Mitral Regurgitation: The Doppler-Echocardiographic Study Revisited. Journal of the Medical Association of Thailand Vol.105 No.12 (2022) , 1208-1215. 1215. doi:10.35755/jmedassocthai.2022.12.13712 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/85190
Title
Pulmonary Hypertension in Mitral Valve Disease-Rheumatic Mitral Stenosis versus Organic Mitral Regurgitation: The Doppler-Echocardiographic Study Revisited
Author's Affiliation
Other Contributor(s)
Abstract
Background: Pulmonary hypertension (PH) is common in patients with mitral valve disease. Objective: To determine the factors associated with PH among patients with mitral valve disease, and the similarities and differences in the subgroups of mitral stenosis (MS) and mitral regurgitation (MR). Materials and Methods: Patients with isolated moderate to severe organic mitral valve disease were prospectively enrolled. PH was defined echocardiographically as pulmonary artery systolic pressure of more than 50 mmHg. Patients with MS who had mitral valve area of more than 1.5 cm2 and patients with MR who had effective regurgitant orifice area of less than 20 mm2 were excluded. Results: Three hundred eighteen patients with a mean age of 54.3±15.5 years including 57.6% female and 66.7% MR were included in this study. PH was present in 119 patients (37.4%), including 48.1% in MS and 31.8% in MR. Severe mitral valve disease was reported in 245 patients (77.0%). Left atrial (LA) diameter and pulmonary artery pressure were significantly higher in patients with MS. Dyspnea, LA volume index, significant tricuspid and pulmonary regurgitation, severe mitral valve disease, and the presence of MS were independently associated with PH. Among patients with MS, LA volume index and severe disease were independently associated with PH. Significant tricuspid and pulmonary regurgitation, LA volume index and severe disease were independently associated with PH in patients with MR. Conclusion: PH is common in patients with mitral valve disease. LA volume index and severe disease were, in common, independently associated with PH in patients with mitral valve disease and in the subgroups of MS and MR.