Molecular markers for malaria genetic epidemiology: progress and pitfalls
Issued Date
2023-01-01
Resource Type
ISSN
14714922
eISSN
14715007
Scopus ID
2-s2.0-85181037758
Pubmed ID
38129280
Journal Title
Trends in Parasitology
Rights Holder(s)
SCOPUS
Bibliographic Citation
Trends in Parasitology (2023)
Suggested Citation
Ruybal-Pesántez S., McCann K., Vibin J., Siegel S., Auburn S., Barry A.E. Molecular markers for malaria genetic epidemiology: progress and pitfalls. Trends in Parasitology (2023). doi:10.1016/j.pt.2023.11.006 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/95514
Title
Molecular markers for malaria genetic epidemiology: progress and pitfalls
Corresponding Author(s)
Other Contributor(s)
Abstract
Over recent years, progress in molecular markers for genotyping malaria parasites has enabled informative studies of epidemiology and transmission dynamics. Results have highlighted the value of these tools for surveillance to support malaria control and elimination strategies. There are many different types and panels of markers available for malaria parasite genotyping, and for end users, the nuances of these markers with respect to ‘use case’, resolution, and accuracy, are not well defined. This review clarifies issues surrounding different molecular markers and their application to malaria control and elimination. We describe available marker panels, use cases, implications for different transmission settings, limitations, access, cost, and data accuracy. The information provided can be used as a guide for molecular epidemiology and surveillance of malaria.