A low- dose of caffeine suppresses EEG alpha power and improves working memory in healthy University males
Issued Date
2022-11-01
Resource Type
ISSN
00319384
eISSN
1873507X
Scopus ID
2-s2.0-85137770147
Pubmed ID
36055414
Journal Title
Physiology and Behavior
Volume
256
Rights Holder(s)
SCOPUS
Bibliographic Citation
Physiology and Behavior Vol.256 (2022)
Suggested Citation
Ajjimaporn A., Noppongsakit P., Ramyarangsi P., Siripornpanich V., Chaunchaiyakul R. A low- dose of caffeine suppresses EEG alpha power and improves working memory in healthy University males. Physiology and Behavior Vol.256 (2022). doi:10.1016/j.physbeh.2022.113955 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/86694
Title
A low- dose of caffeine suppresses EEG alpha power and improves working memory in healthy University males
Author's Affiliation
Other Contributor(s)
Abstract
The effects of a low dose of caffeine, administered in the morning, on brain wave activity and cognitive function were investigated in 25 healthy university Southeast Asian men (mean age ±standard deviation: 21 ± 2 years). Participants received a placebo (PLA) or a 50 mg caffeinated drink (CAF) under randomized, double-blind crossover conditions, with 1 week between conditions. Brain wave activity was assessed using electroencephalography (EEG) from a 5 min eyes-closed resting state. Cognitive function, i.e., visuomotor processing speed, working memory, and attention were assessed using the trail-making test A (Trails A) and B (Trails B), and digit span Forwards (DF), respectively. All tests were examined before drinking (BD), 30 min after drinking (AD), and 35 min after 5-min isokinetic exercise (AE). [Results] The CAF showed a significant decrease in the percentage changes from baseline (%∆) of alpha wave activity over the midline electrodes, i.e., frontal, central, and occipital areas after AD (p<0.05). Data from cognitive function tests were significantly improved after AD (p<0.05). A significant inverse correlation between the diminished alpha wave activity over the midline central and occipital cortical regions and the Trails B positive scores were observed (p<0.05). [Conclusion] The diminishment in resting alpha wave activity and improvement of cognitive function on working memory assessed by the Trails B following caffeine consumption would support the stimulant effects of low-dose caffeine as a morning wake-up drink in young adults.