Global trend of food-induced anaphylaxis: Up to date
2
Issued Date
2025-12-01
Resource Type
ISSN
09056157
eISSN
13993038
Scopus ID
2-s2.0-105023593031
Pubmed ID
41332221
Journal Title
Pediatric Allergy and Immunology
Volume
36
Issue
12
Rights Holder(s)
SCOPUS
Bibliographic Citation
Pediatric Allergy and Immunology Vol.36 No.12 (2025)
Suggested Citation
Leung A.S.y., Estrada-Reyes E., Goto K., Huang C.H., Li J.M., Nagarajan S.A., Ranasinghe T., Sato S., Srisuwatchari W., Zepeda-Ortega B., Tham E.H. Global trend of food-induced anaphylaxis: Up to date. Pediatric Allergy and Immunology Vol.36 No.12 (2025). doi:10.1111/pai.70246 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/113452
Title
Global trend of food-induced anaphylaxis: Up to date
Author's Affiliation
Chinese University of Hong Kong
NUS Yong Loo Lin School of Medicine
Siriraj Hospital
St. Marianna University School of Medicine
Chinese University of Hong Kong, Faculty of Medicine
University of Sri Jayewardenepura
National Hospital Organization Sagamihara National Hospital
Hospital Angeles Metropolitano
Motherhood Hospital
Private Practice
NUS Yong Loo Lin School of Medicine
Siriraj Hospital
St. Marianna University School of Medicine
Chinese University of Hong Kong, Faculty of Medicine
University of Sri Jayewardenepura
National Hospital Organization Sagamihara National Hospital
Hospital Angeles Metropolitano
Motherhood Hospital
Private Practice
Corresponding Author(s)
Other Contributor(s)
Abstract
This review examines the evolving global landscape of food-induced anaphylaxis (FIA), revealing critical epidemiological shifts that challenge traditional allergen management paradigms. As the leading cause of anaphylaxis worldwide, FIA demonstrates striking geographic, age-specific, and temporal patterns that reflect broader changes in dietary practices, environmental exposures, and food production systems. Emerging trends reveal novel allergen sources that evade current regulatory frameworks, including non-priority legumes, edible insects and galacto-oligosaccharides with distinct cross-reactivity patterns and the expanding prevalence of buckwheat, tree nut and seeds anaphylaxis. Complex syndromes such as lipid transfer protein syndrome, tick-borne α-Gal syndrome and food-dependent exercise-induced anaphylaxis represent diagnostic challenges requiring heightened clinical suspicion. Critical knowledge gaps remain in certain regions where limited surveillance, inadequate adrenaline access, and uncharacterized regional allergens create substantial management disparities. The review emphasizes urgent needs for comprehensive global surveillance networks, precision diagnostic tools for atypical presentations, expanded allergen labeling policies encompassing novel proteins, and equity-centered interventions addressing geographic disparities in emergency treatment access. (Figure presented.).