Joint Asian Pacific Association of Gastroenterology (APAGE)-Asian Pacific Society of Digestive Endoscopy (APSDE) clinical practice guidelines on the use of non-invasive biomarkers for diagnosis of colorectal neoplasia
Issued Date
2023-01-01
Resource Type
ISSN
00175749
eISSN
14683288
Scopus ID
2-s2.0-85160243437
Pubmed ID
37019620
Journal Title
Gut
Rights Holder(s)
SCOPUS
Bibliographic Citation
Gut (2023)
Suggested Citation
Chan F.K.L., Wong M.C.S., Chan A.T., East J.E., Chiu H.M., Makharia G.K., Weller D., Ooi C.J., Limsrivilai J., Saito Y., Hang D.V., Emery J.D., Makmun D., Wu K., Ali R.A.R., Ng S.C. Joint Asian Pacific Association of Gastroenterology (APAGE)-Asian Pacific Society of Digestive Endoscopy (APSDE) clinical practice guidelines on the use of non-invasive biomarkers for diagnosis of colorectal neoplasia. Gut (2023). doi:10.1136/gutjnl-2023-329429 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/82969
Title
Joint Asian Pacific Association of Gastroenterology (APAGE)-Asian Pacific Society of Digestive Endoscopy (APSDE) clinical practice guidelines on the use of non-invasive biomarkers for diagnosis of colorectal neoplasia
Author's Affiliation
Siriraj Hospital
Edinburgh Medical School
Sunway University
Duke-NUS Medical School
National Taiwan University Hospital
Hanoi Medical University
Xijing Hospital
Universitas Indonesia
Harvard T.H. Chan School of Public Health
Massachusetts General Hospital
Faculty of Medicine, Dentistry and Health Sciences
National Cancer Center Hospital
All India Institute of Medical Sciences, New Delhi
Nuffield Department of Medicine
Chinese University of Hong Kong
Harvard Medical School
Mayo Clinic Healthcare
Edinburgh Medical School
Sunway University
Duke-NUS Medical School
National Taiwan University Hospital
Hanoi Medical University
Xijing Hospital
Universitas Indonesia
Harvard T.H. Chan School of Public Health
Massachusetts General Hospital
Faculty of Medicine, Dentistry and Health Sciences
National Cancer Center Hospital
All India Institute of Medical Sciences, New Delhi
Nuffield Department of Medicine
Chinese University of Hong Kong
Harvard Medical School
Mayo Clinic Healthcare
Other Contributor(s)
Abstract
Screening for colorectal cancer (CRC) is effective in reducing CRC related mortality. Current screening methods include endoscopy based and biomarker based approaches. This guideline is a joint official statement of the Asian Pacific Association of Gastroenterology (APAGE) and the Asian Pacific Society of Digestive Endoscopy (APSDE), developed in response to the increasing use of, and accumulating supportive evidence for the role of, non-invasive biomarkers for the diagnosis of CRC and its precursor lesions. A systematic review of 678 publications and a two stage Delphi consensus process involving 16 clinicians in various disciplines was undertaken to develop 32 evidence based and expert opinion based recommendations for the use of faecal immunochemical tests, faecal based tumour biomarkers or microbial biomarkers, and blood based tumour biomarkers for the detection of CRC and adenoma. Comprehensive up-to-date guidance is provided on indications, patient selection and strengths and limitations of each screening tool. Future research to inform clinical applications are discussed alongside objective measurement of research priorities. This joint APAGE-APSDE practice guideline is intended to provide an up-to-date guide to assist clinicians worldwide in utilising non-invasive biomarkers for CRC screening; it has particular salience for clinicians in the Asia-Pacific region.