mBAT: a newly developed mobile application for self-screening of pediatric bleeding disorders – a multi-center study
Issued Date
2025-01-01
Resource Type
ISSN
09395555
eISSN
14320584
Scopus ID
2-s2.0-85217232064
Pubmed ID
39812819
Journal Title
Annals of Hematology
Rights Holder(s)
SCOPUS
Bibliographic Citation
Annals of Hematology (2025)
Suggested Citation
Sermcheep A., Natesirinilkul R., Komvilaisak P., Songthawee N., Laohverapanich K., Songdej D., Wongwerawattanakoon P., Kadegasem P., Chuansumrit A., Sirachainan N. mBAT: a newly developed mobile application for self-screening of pediatric bleeding disorders – a multi-center study. Annals of Hematology (2025). doi:10.1007/s00277-024-06178-w Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/105303
Title
mBAT: a newly developed mobile application for self-screening of pediatric bleeding disorders – a multi-center study
Corresponding Author(s)
Other Contributor(s)
Abstract
Bleeding assessment tools (BATs) are used by trained medical personnel for screening bleeding disorders on a one-to-one basis with patients; hence, they are time-consuming and limited in use for large-population screening. The aims of the study were to develop, validate, and demonstrate a Thai BAT mobile application (mBAT) for self-screening of bleeding disorders. mBAT was developed and validated using the paper-based Thai version of pediatric bleeding questionnaire (TPBQ). Then, mBAT was applied to 916 subjects from communities and hematology clinics. Those with scores of ≥3 consented to further investigation of bleeding disorders. mBAT was developed for Thai children using simple sentences, a video introduction, pictures, and auto-calculation. It showed a high correlation with the TPBQ: r = 0.96 and 0.97 in the PBQ and ISTH scoring systems, respectively (P<0.01). A score ≥3 was considered abnormal. The mBAT was applied to 916 subjects, with a mean (range) age of 10.5 (0.07-18.0) years. Most subjects (97.3%) were from the community, and the rest (2.7%) were from hematology clinics. The results showed 41 subjects had abnormal scores, and 35 (16 from the community and 19 from clinics) consented to diagnostic investigation. Eleven subjects (31.4%) were found to have bleeding disorders, including four with VWD, two each with hemophilia A and thrombocytopenia, and one each with factor VII deficiency, platelet dysfunction, and MYH9-related disorder. Thus, the prevalence rates of bleeding disorders in the subjects whose scores ≥3 from community and hematology clinics were 6.25% and 52.6%, respectively. In conclusions, the mBAT had a high correlation with the TPBQ. As a self-screening tool, it could enhance the diagnosis of bleeding disorders.