Health inequality and improvement gap in the prevalence of gynecological cancers among perimenopausal women globally, 1990-2019
Issued Date
2025-02-12
Resource Type
eISSN
14712458
Scopus ID
2-s2.0-85218482815
Pubmed ID
39939993
Journal Title
BMC public health
Volume
25
Issue
1
Rights Holder(s)
SCOPUS
Bibliographic Citation
BMC public health Vol.25 No.1 (2025) , 590
Suggested Citation
Yang C., Zou J., Luo X., Ou Y., Lin X., Wang X., Guan Q., Zeng F., Liang D., Lin X. Health inequality and improvement gap in the prevalence of gynecological cancers among perimenopausal women globally, 1990-2019. BMC public health Vol.25 No.1 (2025) , 590. doi:10.1186/s12889-025-21807-3 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/105528
Title
Health inequality and improvement gap in the prevalence of gynecological cancers among perimenopausal women globally, 1990-2019
Corresponding Author(s)
Other Contributor(s)
Abstract
BACKGROUND: Perimenopausal women are a high-risk group for gynecological cancers; however, the spatiotemporal heterogeneity in prevalence and its association with socioeconomic development have not been fully explored. This study aimed to analyze the global burden of cervical, ovarian, and uterine cancers among perimenopausal women, examine health inequalities, and investigate their relationship with socioeconomic levels. METHODS: We assessed the disease burden of gynecological cancers in perimenopausal women using the 2019 Global Burden of Disease study (GBD2019) data, utilizing prevalence and Years of Life Lost (YLL) rates. Health inequality and frontier analyses were performed based on age-standardized prevalence rates for cervical, ovarian, and uterine cancers, coupled with associated socio-demographic index (SDI) data. RESULTS: Over the past thirty years, global prevalence rates of cervical, ovarian, and uterine cancers among perimenopausal women have risen, while the number of YLLs has declined. Correlation analysis with the SDI showed that ovarian and uterine cancer prevalence rates positively correlated with SDI, whereas cervical cancer prevalence was inversely related to it. Moreover, the burden of these cancers demonstrated marked inequalities in relation to SDI, with cervical cancer disparities intensifying-the absolute value of the inequality slope index rose from 100.98 in 1990 to 170.17 in 2019. Ovarian cancer experienced a slight decrease in inequalities, while uterine cancer saw a significant increase, with its inequality slope index jumping from 176.51 in 1990 to 226.01 in 2019. Additionally, there existed regional health disparities in the disease burden of ovarian cancer among perimenopausal women; notably, in regions where YLLs rates for ovarian cancer were increasing, economically developed areas actually exhibited a decline. CONCLUSION: Globally, the prevalence of gynecological cancers in perimenopausal women showed an increasing trend. The health inequality gap for cervical and uterine cancer has widened, while disparities in ovarian cancer are particularly pronounced across regions. There remains scope for improvement in managing the prevalence of gynecological cancers among perimenopausal women across countries with varying SDI levels.