Statement from the frontal fibrosing alopecia international expert alliance: SOFFIA 2024
Issued Date
2025-01-01
Resource Type
ISSN
09269959
eISSN
14683083
Scopus ID
2-s2.0-105012477537
Pubmed ID
40698981
Journal Title
Journal of the European Academy of Dermatology and Venereology
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the European Academy of Dermatology and Venereology (2025)
Suggested Citation
Meah N., Li J., Wall D., York K., Bhoyrul B., Bokhari L., Coulthard L., Asfour L., Abraham L.S., Asz-Sigall D., Bergfeld W.F., Betz R.C., Blume-Peytavi U., Callender V., Chitreddy V., Combalia A., Cotsarelis G., Craiglow B., Dhurat R., Dlova N., Donovan J., Doroshkevich A., Eisman S., Farrant P., Gadzhigoroeva A., Green J., Grimalt R., Harries M., Hordinsky M., Irvine A.D., Jolliffe V., Kaiumov S., King B., Kossard S., Lee J., Lee W.S., Lortkipanidze N., McMichael A., Atanaskova Mesinkovska N., Messenger A., Mirmirani P., Olsen E., Orlow S.J., Ovcharenko Y., Piraccini B.M., Pirmez R., Rakowska A., Reygagne P., Roberts J., Rudnicka L., Saceda-Corralo D., Shapiro J., Sharma P., Silyuk T., Suchonwanit P., Takwale A., Tosti A., Visser W.I., Vañó-Galván S., Vogt A., Wade M., Yip L., Zlotogorski A., Zhou C., Sinclair R. Statement from the frontal fibrosing alopecia international expert alliance: SOFFIA 2024. Journal of the European Academy of Dermatology and Venereology (2025). doi:10.1111/jdv.20833 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/111616
Title
Statement from the frontal fibrosing alopecia international expert alliance: SOFFIA 2024
Author(s)
Meah N.
Li J.
Wall D.
York K.
Bhoyrul B.
Bokhari L.
Coulthard L.
Asfour L.
Abraham L.S.
Asz-Sigall D.
Bergfeld W.F.
Betz R.C.
Blume-Peytavi U.
Callender V.
Chitreddy V.
Combalia A.
Cotsarelis G.
Craiglow B.
Dhurat R.
Dlova N.
Donovan J.
Doroshkevich A.
Eisman S.
Farrant P.
Gadzhigoroeva A.
Green J.
Grimalt R.
Harries M.
Hordinsky M.
Irvine A.D.
Jolliffe V.
Kaiumov S.
King B.
Kossard S.
Lee J.
Lee W.S.
Lortkipanidze N.
McMichael A.
Atanaskova Mesinkovska N.
Messenger A.
Mirmirani P.
Olsen E.
Orlow S.J.
Ovcharenko Y.
Piraccini B.M.
Pirmez R.
Rakowska A.
Reygagne P.
Roberts J.
Rudnicka L.
Saceda-Corralo D.
Shapiro J.
Sharma P.
Silyuk T.
Suchonwanit P.
Takwale A.
Tosti A.
Visser W.I.
Vañó-Galván S.
Vogt A.
Wade M.
Yip L.
Zlotogorski A.
Zhou C.
Sinclair R.
Li J.
Wall D.
York K.
Bhoyrul B.
Bokhari L.
Coulthard L.
Asfour L.
Abraham L.S.
Asz-Sigall D.
Bergfeld W.F.
Betz R.C.
Blume-Peytavi U.
Callender V.
Chitreddy V.
Combalia A.
Cotsarelis G.
Craiglow B.
Dhurat R.
Dlova N.
Donovan J.
Doroshkevich A.
Eisman S.
Farrant P.
Gadzhigoroeva A.
Green J.
Grimalt R.
Harries M.
Hordinsky M.
Irvine A.D.
Jolliffe V.
Kaiumov S.
King B.
Kossard S.
Lee J.
Lee W.S.
Lortkipanidze N.
McMichael A.
Atanaskova Mesinkovska N.
Messenger A.
Mirmirani P.
Olsen E.
Orlow S.J.
Ovcharenko Y.
Piraccini B.M.
Pirmez R.
Rakowska A.
Reygagne P.
Roberts J.
Rudnicka L.
Saceda-Corralo D.
Shapiro J.
Sharma P.
Silyuk T.
Suchonwanit P.
Takwale A.
Tosti A.
Visser W.I.
Vañó-Galván S.
Vogt A.
Wade M.
Yip L.
Zlotogorski A.
Zhou C.
Sinclair R.
Author's Affiliation
University of Minnesota Twin Cities
The University of British Columbia
University of Melbourne
Alma Mater Studiorum Università di Bologna
Yale School of Medicine
The University of Sheffield
Charité – Universitätsmedizin Berlin
Cleveland Clinic Foundation
University of Pennsylvania Perelman School of Medicine
University College Dublin
NYU Grossman School of Medicine
University of Miami Leonard M. Miller School of Medicine
Trinity College Dublin
University of KwaZulu-Natal
Hospital Clínic de Barcelona
Wake Forest University School of Medicine
Universidade de Brasília
Barts and The London School of Medicine and Dentistry
UCI School of Medicine
Medical University of Warsaw
Universidad de Alcalá
Kaiser Permanente
Hôpital Saint-Louis
Universitätsklinikum Bonn
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hospital Universitario Ramón y Cajal
Faculty of Biology, Medicine and Health
Peking University People's Hospital
St. Vincent's Hospital Melbourne
Faculty of Medicine
Yonsei University Mirae Campus
Stellenbosch University, Faculty of Medicine and Health Sciences
Salford Royal Hospital
Ramathibodi Hospital
Mater Misericordiae University Hospital
Howard University College of Medicine
Universitat Internacional de Catalunya
Salford Royal NHS Foundation Trust
University Hospitals Sussex NHS Foundation Trust
Hospital General "Dr. Manuel Gea González"
Lokmanya Tilak Municipal Medical College
Lancashire Teaching Hospitals NHS Foundation Trust
Box Hill Hospital
National Skin Centre, Singapore
Gloucestershire Hospitals NHS Foundation Trust
BlackRock, Inc.
Santa Casa da Misericórdia do Rio de Janeiro
David Tvildiani Medical University
Skin Health Institute
Hospital Regional da Asa Norte
Callender Dermatology and Cosmetic Center
Donovan Hair Clinic
Sinclair Dermatology
Hair Treatment and Transplantation Center
The London Skin and Hair Clinic
Duke Dermatology Clinic
Skin Partners Specialist Dermatologists
Northwest Dermatology Institute
Kossard Dermatopathologists
#TricoHRC Research Group
LLC «Institute of Beautiful Hair»
Nautilus Clinic and Education Centre
Beachside Specialist Group
Scientific & Practical Center Dermatolovenereology and Cosmetology of the Moscow City Health Department
The University of British Columbia
University of Melbourne
Alma Mater Studiorum Università di Bologna
Yale School of Medicine
The University of Sheffield
Charité – Universitätsmedizin Berlin
Cleveland Clinic Foundation
University of Pennsylvania Perelman School of Medicine
University College Dublin
NYU Grossman School of Medicine
University of Miami Leonard M. Miller School of Medicine
Trinity College Dublin
University of KwaZulu-Natal
Hospital Clínic de Barcelona
Wake Forest University School of Medicine
Universidade de Brasília
Barts and The London School of Medicine and Dentistry
UCI School of Medicine
Medical University of Warsaw
Universidad de Alcalá
Kaiser Permanente
Hôpital Saint-Louis
Universitätsklinikum Bonn
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hospital Universitario Ramón y Cajal
Faculty of Biology, Medicine and Health
Peking University People's Hospital
St. Vincent's Hospital Melbourne
Faculty of Medicine
Yonsei University Mirae Campus
Stellenbosch University, Faculty of Medicine and Health Sciences
Salford Royal Hospital
Ramathibodi Hospital
Mater Misericordiae University Hospital
Howard University College of Medicine
Universitat Internacional de Catalunya
Salford Royal NHS Foundation Trust
University Hospitals Sussex NHS Foundation Trust
Hospital General "Dr. Manuel Gea González"
Lokmanya Tilak Municipal Medical College
Lancashire Teaching Hospitals NHS Foundation Trust
Box Hill Hospital
National Skin Centre, Singapore
Gloucestershire Hospitals NHS Foundation Trust
BlackRock, Inc.
Santa Casa da Misericórdia do Rio de Janeiro
David Tvildiani Medical University
Skin Health Institute
Hospital Regional da Asa Norte
Callender Dermatology and Cosmetic Center
Donovan Hair Clinic
Sinclair Dermatology
Hair Treatment and Transplantation Center
The London Skin and Hair Clinic
Duke Dermatology Clinic
Skin Partners Specialist Dermatologists
Northwest Dermatology Institute
Kossard Dermatopathologists
#TricoHRC Research Group
LLC «Institute of Beautiful Hair»
Nautilus Clinic and Education Centre
Beachside Specialist Group
Scientific & Practical Center Dermatolovenereology and Cosmetology of the Moscow City Health Department
Corresponding Author(s)
Other Contributor(s)
Abstract
Background: As the incidence of frontal fibrosing alopecia (FFA) continues to rise, there is a need for an optimal treatment algorithm for FFA. Objective: To produce an international consensus statement on the treatment modalities and prognostic indicators of FFA. Methods: Sixty-nine hair experts from six continents were invited to participate in a three-round Delphi process. The final stage was held as a virtual meeting facilitated via Zoom. The consensus threshold was set at ≥66%. Results: Of 365 questions, expert consensus was achieved in 204 (56%) questions following completion of the three rounds. Three additional questions were included at the final meeting. The category with the strongest consensus agreement was disease monitoring (9; 100%). Questions pertaining to physical therapies achieved the least category consensus (15; 40%), followed by systemic therapy (45; 43%). Limitations: The study lacked sufficient representation from Africa and South America. Conclusion: SOFFIA highlights areas of agreement and disagreement among experts. Robust research is warranted to provide evidence-based treatment recommendations.