Defining exposure for estimating the global burden of alcohol consumption: plausibility testing of WHO methodology using ASEAN countries as a case study

dc.contributor.authorRehm J.
dc.contributor.authorAmul G.G.H.
dc.contributor.authorAssanangkornchai S.
dc.contributor.authorChaiyasong S.
dc.contributor.authorCorreia D.
dc.contributor.authorHairi N.N.
dc.contributor.authorHanafi E.
dc.contributor.authorHassan A.S.
dc.contributor.authorHtet K.K.K.
dc.contributor.authorLow W.Y.
dc.contributor.authorMedina J.R.C.
dc.contributor.authorNontarak J.
dc.contributor.authorOng S.K.
dc.contributor.authorRovira P.
dc.contributor.authorSiste K.
dc.contributor.authorSornpaisarn B.
dc.contributor.authorSychareun V.
dc.contributor.authorTong W.T.
dc.contributor.authorVichitkunakorn P.
dc.contributor.authorYi S.
dc.contributor.authorZayar N.N.
dc.contributor.authorShield K.
dc.contributor.correspondenceRehm J.
dc.contributor.otherMahidol University
dc.date.accessioned2026-03-03T18:51:35Z
dc.date.available2026-03-03T18:51:35Z
dc.date.issued2026-12-01
dc.description.abstractBackground: Comparative risk assessments (CRAs) provide important information for shaping alcohol control policies. Underlying their CRAs, the WHO uses a standardised methodology to assess and detail the levels of alcohol use for all countries and for various regions. This publication uses a case study approach on the member states of the Association of South East Asian Nations (ASEAN) to examine potential biases resulting from the methodology employed by the WHO in calculating exposure values for their CRAs. Methods: Researchers from each of the 10 ASEAN member states identified large population surveys to improve upon the data collected by the WHO monitoring systems to estimate exposure between 2000 and 2022. From these surveys and aggregate data, key indicators were created for each Member State using WHO standardised methodology. Steps were defined to test for implausible values, particularly for the indicator for average level of alcohol consumption among drinkers. Sensitivity analyses were undertaken to identify possible causes of these values. Finally, we compared the results of the implausibility checks with two other regions, the European Union (EU) and the East African Community (EAC), based on data collected by the WHO. Results: The indicator for average volume of alcohol consumption among drinkers showed implausibly high values for three ASEAN countries, Lao PDR, Thailand and Viet Nam. Further simulations based on assumptions regarding the prevalence of people with heavy or very heavy drinking levels further corroborated a likely bias. An examination of the constituents of the indicator revealed that the bias for Thailand could be due to responses received to survey questions regarding alcohol abstention, in which a high number of respondents claimed no consumption of alcohol over the past year. For the Lao PDR and Viet Nam, the same problem with survey respondent self-reports on alcohol consumption may exist, but we cannot exclude the possibility that answers to the survey question regarding unrecorded alcohol may also have contributed. Investigations of two further regions of the world also showed some implausible values, albeit to a smaller degree for the EU. Conclusions: Plausibility testing of key monitoring indicators is important and yields important information for improving future monitoring efforts.
dc.identifier.citationSubstance Abuse Treatment Prevention and Policy Vol.21 No.1 (2026)
dc.identifier.doi10.1186/s13011-026-00703-y
dc.identifier.eissn1747597X
dc.identifier.scopus2-s2.0-105031108681
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/115523
dc.rights.holderSCOPUS
dc.subjectMedicine
dc.titleDefining exposure for estimating the global burden of alcohol consumption: plausibility testing of WHO methodology using ASEAN countries as a case study
dc.typeArticle
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=105031108681&origin=inward
oaire.citation.issue1
oaire.citation.titleSubstance Abuse Treatment Prevention and Policy
oaire.citation.volume21
oairecerif.author.affiliationUniversity of Toronto
oairecerif.author.affiliationNational University of Singapore
oairecerif.author.affiliationChinese University of Hong Kong
oairecerif.author.affiliationUniversity of Toronto Faculty of Medicine
oairecerif.author.affiliationUniversidade do Porto
oairecerif.author.affiliationUniversiti Malaya
oairecerif.author.affiliationUniversitätsklinikum Hamburg-Eppendorf
oairecerif.author.affiliationMahidol University
oairecerif.author.affiliationPrince of Songkla University
oairecerif.author.affiliationCentre for Addiction and Mental Health
oairecerif.author.affiliationSchulich School of Medicine & Dentistry
oairecerif.author.affiliationUniversiti Brunei Darussalam
oairecerif.author.affiliationMahasarakham University
oairecerif.author.affiliationUniversitas Indonesia, RSUPN Dr. Cipto Mangunkusumo
oairecerif.author.affiliationFaculty of Medicine, Prince of Songkla University
oairecerif.author.affiliationAgencia de Salut Publica de Barcelona
oairecerif.author.affiliationWHO Regional Office for Europe
oairecerif.author.affiliationNational Institutes of Health, University of the Philippines Manila
oairecerif.author.affiliationKHANA
oairecerif.author.affiliationLaboratório para a Investigação Integrativa e Translacional em Saúde Populacional (ITR)
oairecerif.author.affiliationMinistry of Health Brunei
oairecerif.author.affiliationUniversity of Health Sciences
oairecerif.author.affiliationPAHO/WHO Collaborating Centre at CAMH
oairecerif.author.affiliationFORUT
oairecerif.author.affiliationUniversity Katipunan Avenue

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