Bifunctional Electrospun PAN/ε-Polylysine Composite Membranes for High-Efficiency PM2.5and PM10Filtration with Antimicrobial Protection
Issued Date
2025-11-11
Resource Type
eISSN
24701343
Scopus ID
2-s2.0-105021273603
Journal Title
ACS Omega
Volume
10
Issue
44
Start Page
53503
End Page
53515
Rights Holder(s)
SCOPUS
Bibliographic Citation
ACS Omega Vol.10 No.44 (2025) , 53503-53515
Suggested Citation
Muadtrap M., Khampieng T., Choipang C., Ngamplang P., Phuking P., Chaiarwut S., Intarapong P., Supaphol P. Bifunctional Electrospun PAN/ε-Polylysine Composite Membranes for High-Efficiency PM2.5and PM10Filtration with Antimicrobial Protection. ACS Omega Vol.10 No.44 (2025) , 53503-53515. 53515. doi:10.1021/acsomega.5c09034 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/113116
Title
Bifunctional Electrospun PAN/ε-Polylysine Composite Membranes for High-Efficiency PM2.5and PM10Filtration with Antimicrobial Protection
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
Airborne particulate matter (PM<inf>2.5</inf>and PM<inf>10</inf>) and bioaerosols pose synergistic threats to respiratory health, necessitating advanced filtration technologies that simultaneously address particulate and microbial contamination. We report a bifunctional multilayer composite air filter membrane fabricated by electrospinning polyacrylonitrile (PAN) nanofibers (average diameter 609 ± 88 nm) onto nonwoven substrates integrated with ε-poly-l-lysine (ε-PL) antimicrobial coating. Optimized electrospinning conditions (10 wt % PAN, 15 min deposition) yielded uniform, bead-free nanofibers achieving exceptional filtration efficiencies of 99.39 ± 0.09% for PM<inf>2.5</inf>and 99.50 ± 0.16% for PM<inf>10</inf>, while maintaining low pressure drop (175 ± 5 Pa) suitable for respiratory applications. The ε-PL coating, immobilized via PVA-mediated adhesion, transformed the hydrophobic spunbond surface to hydrophilic (contact angle reduced from 108° to 48°) and conferred potent antimicrobial activity. Time-kill assays demonstrated concentration-dependent bactericidal effects, with 10 mg/mL ε-PL achieving complete bacterial eradication (>6-log reduction) within 24 h against both Gram-positive and Gram-negative pathogens. Comparative analysis revealed superior performance over commercial multilayer masks (66–98% efficiency for PM<inf>2.5</inf>; 66–98% efficiency for PM<inf>10</inf>), despite lower basis weight (94.01 ± 1.95 g/m<sup>2</sup>). The quality factor analysis confirmed optimal balance between high filtration efficiency and breathability at 15 min electrospinning time. These dual-functional membranes demonstrate the synergistic integration of high-efficiency particulate filtration across multiple size fractions with antimicrobial protection, offering a promising platform for personal protective equipment, HVAC systems, and healthcare air purification applications where simultaneous removal of coarse and fine airborne particles and pathogen inactivation is critical.