Diverse Malaria Presentations across National Institutes of Health South Asia International Center for Excellence in Malaria Research Sites in India
Issued Date
2022-10-01
Resource Type
ISSN
00029637
eISSN
14761645
Scopus ID
2-s2.0-85139812716
Pubmed ID
36228910
Journal Title
American Journal of Tropical Medicine and Hygiene
Volume
107
Start Page
107
End Page
117
Rights Holder(s)
SCOPUS
Bibliographic Citation
American Journal of Tropical Medicine and Hygiene Vol.107 (2022) , 107-117
Suggested Citation
Chakrabarti R., Chery-Karschney L., White J., Mascarenhas A., Skillman K.M., Kanjee U., Babar P.H., Patrapuvich R., Mohapatra P.K., Patankar S., Smith J.D., Anvikar A., Valecha N., Rahi M., Duraisingh M.T., Rathod P.K. Diverse Malaria Presentations across National Institutes of Health South Asia International Center for Excellence in Malaria Research Sites in India. American Journal of Tropical Medicine and Hygiene Vol.107 (2022) , 107-117. 117. doi:10.4269/ajtmh.21-1344 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/87229
Title
Diverse Malaria Presentations across National Institutes of Health South Asia International Center for Excellence in Malaria Research Sites in India
Author's Affiliation
Faculty of Tropical Medicine, Mahidol University
Harvard T.H. Chan School of Public Health
Indian Council of Medical Research
National Institute of Malaria Research India
Goa Medical College & Hospital
Children's Hospital and Regional Medical Center
University of Washington
Indian Institute of Technology Bombay
Regional Medical Research Center-Northeast Region (RMRC-NE)
National Institute of Biologicals
Harvard T.H. Chan School of Public Health
Indian Council of Medical Research
National Institute of Malaria Research India
Goa Medical College & Hospital
Children's Hospital and Regional Medical Center
University of Washington
Indian Institute of Technology Bombay
Regional Medical Research Center-Northeast Region (RMRC-NE)
National Institute of Biologicals
Other Contributor(s)
Abstract
The Malaria Evolution in South Asia (MESA) International Center for Excellence in Malaria Research (ICEMR) was established by the US National Institutes of Health (US NIH) as one of 10 malaria research centers in endemic countries. In 10 years of hospital-based and field-based work in India, the MESA-ICEMR has documented the changing epidemiology and transmission of malaria in four different parts of India. Malaria Evolution in South Asia-ICEMR activities, in collaboration with Indian partners, are carried out in the broad thematic areas of malaria case surveillance, vector biology and transmission, antimalarial resistance, pathogenesis, and host response. The program integrates insights from surveillance and field studies with novel basic science studies. This is a two-pronged approach determining the biology behind the disease patterns seen in the field, and generating new relevant biological questions about malaria to be tested in the field. Malaria Evolution in South Asia-ICEMR activities inform local and international stakeholders on the current status of malaria transmission in select parts of South Asia including updates on regional vectors of transmission of local parasites. The community surveys and new laboratory tools help monitor ongoing efforts to control and eliminate malaria in key regions of South Asia including the state of evolving antimalarial resistance in different parts of India, new host biomarkers of recent infection, and molecular markers of pathogenesis from uncomplicated and severe malaria.