Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia
Issued Date
2022-01-01
Resource Type
ISSN
19352727
eISSN
19352735
Scopus ID
2-s2.0-85123815919
Pubmed ID
35077452
Journal Title
PLoS Neglected Tropical Diseases
Volume
16
Issue
1
Rights Holder(s)
SCOPUS
Bibliographic Citation
PLoS Neglected Tropical Diseases Vol.16 No.1 (2022)
Suggested Citation
Bigio J. Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia. PLoS Neglected Tropical Diseases Vol.16 No.1 (2022). doi:10.1371/JOURNAL.PNTD.0010028 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/86679
Title
Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia
Author(s)
Author's Affiliation
Faculty of Tropical Medicine, Mahidol University
L'Institut de Recherche du Centre Universitaire de Santé McGill
SOAS University of London
Malaria Consortium
Ministry of Health Cambodia
London School of Hygiene & Tropical Medicine
McGill Faculty of Medicine and Health Sciences
Organisation Mondiale de la Santé
University of Pretoria
James Cook University
AC Investment Co
L'Institut de Recherche du Centre Universitaire de Santé McGill
SOAS University of London
Malaria Consortium
Ministry of Health Cambodia
London School of Hygiene & Tropical Medicine
McGill Faculty of Medicine and Health Sciences
Organisation Mondiale de la Santé
University of Pretoria
James Cook University
AC Investment Co
Other Contributor(s)
Abstract
Cambodia has one of the highest dengue infection rates in Southeast Asia. Here we report quantitative entomological results of a large-scale cluster-randomised trial assessing the impact on vector populations of a package of vector control interventions including larvivorous guppy fish in household water containers, mosquito trapping with gravidovitraps, solid waste management, breeding-container coverage through community education and engagement for behavioural change, particularly through the participation of school children. These activities resulted in major reductions in Container Index, House Index, Breteau Index, Pupal Index and Adult Index (all p-values 0.002 or lower) in the Intervention Arm compared with the Control Arm in a series of household surveys conducted over a follow-up period of more than one year, although the project was not able to measure the longer-term sustainability of the interventions. Despite comparative reductions in Adult Index between the study arms, the Adult Index was higher in the Intervention Arm in the final household survey than in the first household survey. This package of biophysical and community engagement interventions was highly effective in reducing entomological indices for dengue compared with the control group, but caution is required in extrapolating the reduction in household Adult Index to a reduction in the overall population of adult Aedes mosquitoes, and in interpreting the relationship between a reduction in entomological indices and a reduction in the number of dengue cases. The package of interventions should be trialled in other locations.