The Geriatric Nutritional Risk Index predicts amputation after infrapopliteal angioplasty in critical limb ischemia patients
6
Issued Date
2023-01-01
Resource Type
ISSN
10159584
eISSN
02193108
Scopus ID
2-s2.0-85127318341
Pubmed ID
35365390
Journal Title
Asian Journal of Surgery
Volume
46
Issue
1
Start Page
250
End Page
253
Rights Holder(s)
SCOPUS
Bibliographic Citation
Asian Journal of Surgery Vol.46 No.1 (2023) , 250-253
Suggested Citation
Ruangsetakit C., Navikaputra S., Pruekprasert K., Prapassaro T., Puangpunngam N., Hongku K., Hahtapornsawan S., Chinsakchai K., Wongwanit C., Sermsathanasawadi N. The Geriatric Nutritional Risk Index predicts amputation after infrapopliteal angioplasty in critical limb ischemia patients. Asian Journal of Surgery Vol.46 No.1 (2023) , 250-253. 253. doi:10.1016/j.asjsur.2022.03.049 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/85154
Title
The Geriatric Nutritional Risk Index predicts amputation after infrapopliteal angioplasty in critical limb ischemia patients
Author's Affiliation
Other Contributor(s)
Abstract
Objective: To validate the Critical Limb Ischemia Frailty Index (CLIFI), and to identify independent predictors of 2-year amputation-free survival after infrapopliteal endovascular treatment for chronic limb-threatening ischemia (CLTI) in Thai patients. Methods: This retrospective study was conducted during the June 2014 to February 2017 study period. CLTI patients treated with infrapopliteal angioplasty were enrolled and analyzed. A patient was defined as CLIFI positive if two or more of the following criteria were present: Geriatric Nutritional Risk Index (GNRI) < 89.8, low skeletal muscle mass index (<6.87 kg/m2 in males, and <5.46 kg/m2 in females), and/or non-ambulatory status. Kaplan–Meier survival analysis was used to assess 2-year amputation-free survival (AFS), and comparisons were performed using log-rank test. Univariate and multivariate Cox proportional hazards models were used to analyze for significant and independent association, respectively, between preoperative characteristics and AFS. Results: A total of 266 patients and 286 limbs were included. Forty (15.0%) patients were CLIFI positive, and 226 (85.0%) patients were CLIFI negative. The 2-year amputation-free survival rate was 90.3% in the CLIFI positive group, and 86.6% in the CLIFI negative group (p = 0.59). Multivariate analysis revealed the GNRI to be an independent risk factor for amputation within two years after infrapopliteal revascularization (adjusted hazard ratio: 4.87, 95% confidence interval: 1.20–19.70; p = 0.02). Conclusions: The GNRI was found to independently predict 2-year amputation after infrapopliteal angioplasty in Thai CLTI patients; however, the CLIFI was not found to significantly predict 2-year amputation in this patient population.