Synthesis of carbon quantum dots based on hemp leaves and cysteamine for latent fingerprint detection and their potential therapeutic anticancer application
Issued Date
2025-10-07
Resource Type
eISSN
25160230
Scopus ID
2-s2.0-105017961520
Journal Title
Nanoscale Advances
Volume
7
Issue
20
Start Page
6646
End Page
6658
Rights Holder(s)
SCOPUS
Bibliographic Citation
Nanoscale Advances Vol.7 No.20 (2025) , 6646-6658
Suggested Citation
Kampangta R., Saenchoopa A., Obrom W., Thet Tun W.S., Muanprasat C., Maeda K., Suwannapaporn P., Suppaso C., Seemakram W., Boonlue S., Kulchat S. Synthesis of carbon quantum dots based on hemp leaves and cysteamine for latent fingerprint detection and their potential therapeutic anticancer application. Nanoscale Advances Vol.7 No.20 (2025) , 6646-6658. 6658. doi:10.1039/d5na00264h Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/112560
Title
Synthesis of carbon quantum dots based on hemp leaves and cysteamine for latent fingerprint detection and their potential therapeutic anticancer application
Corresponding Author(s)
Other Contributor(s)
Abstract
In this study, an eco-friendly one-pot hydrothermal method was used to synthesize carbon quantum dots (CQDs) using hemp leaves and cysteamine hydrochloride as the carbon and nitrogen-sulfur sources, respectively. Synthesized carbon quantum dots (HC-CQDs) were developed to achieve the clear detection of latent fingerprints (LFPs) on non-porous materials under UV-light, and their nontoxicity to humans was verified by testing on cancer cells. HC-CQDs characterized by various techniques exhibited a high quantum yield of 36.1%, and their excitation and emission peaks appeared at 354 and 434 nm, respectively. For the detection of LFPs, we prepared a fluorescence fingerprint powder utilizing HC-CQDs, cellulose nanofiber (CNF), chitosan, and cassava starch. Results showed a complete fingerprint, and it was possible to clearly identify the location and type of defects on the fingerprint (minutiae). Additionally, we performed MTT assays to understand the effect of HC-CQDs on cell viability in cancer cell lines. HC-CQDs exhibited pronounced anti-cancer activity against A549 lung carcinoma cells while demonstrating negligible cytotoxic effects on normal Vero cells. Therefore, this study successfully developed plant-based fluorescent carbon quantum dots, which can be used to prepare a fluorescent powder for detecting LFPs that is safe for forensic scientists. These HC-CQDs also possess potential in inhibiting A549 lung cancer cells, which could be further developed in the medical field.