Fibrodysplasia Ossificans Progressiva: A Case Report with Pseudo-Ankylosis of the Temporomandibular Joint
Issued Date
2022-01-01
Resource Type
ISSN
10556656
eISSN
15451569
Scopus ID
2-s2.0-85144287592
Pubmed ID
36536588
Journal Title
Cleft Palate-Craniofacial Journal
Rights Holder(s)
SCOPUS
Bibliographic Citation
Cleft Palate-Craniofacial Journal (2022)
Suggested Citation
Chaisrisawadisuk S., Oliver K.J., Constantine S., Azzopardi J., Anderson P.J., Moore M.H. Fibrodysplasia Ossificans Progressiva: A Case Report with Pseudo-Ankylosis of the Temporomandibular Joint. Cleft Palate-Craniofacial Journal (2022). doi:10.1177/10556656221146598 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/84460
Title
Fibrodysplasia Ossificans Progressiva: A Case Report with Pseudo-Ankylosis of the Temporomandibular Joint
Author's Affiliation
Other Contributor(s)
Abstract
Fibrodysplasia ossificans progressiva (FOP) is a rare condition characterized by progressive heterotopic ossifications and congenital hallux valgus deformities. The common underlying genetic cause is an ACVR1 mutation, resulting in altered bone morphogenetic protein (BMP) regulation. Trauma and/or minor procedures aggravate the abnormal bony formation in soft tissues. This report presents a 3-year-old child with this condition who presented pseudo-ankylosis of the temporomandibular joint (TMJ) after minor craniofacial trauma. Abnormal ossification in the medial pterygoid muscle was identified as the causative abnormality for the presentation with trismus.