Oral and Craniofacial Anomalies of Fraser Syndrome: Prosthetic Management
Issued Date
2022-07-01
Resource Type
ISSN
18122027
eISSN
18122078
Scopus ID
2-s2.0-85152297880
Pubmed ID
37042386
Journal Title
Kathmandu University Medical Journal
Volume
20
Issue
79
Start Page
391
End Page
395
Rights Holder(s)
SCOPUS
Bibliographic Citation
Kathmandu University Medical Journal Vol.20 No.79 (2022) , 391-395
Suggested Citation
Amornvit P., Rokaya D., Sapkota D., Sanohkan S. Oral and Craniofacial Anomalies of Fraser Syndrome: Prosthetic Management. Kathmandu University Medical Journal Vol.20 No.79 (2022) , 391-395. 395. doi:10.3126/kumj.v20i3.54017 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/85728
Title
Oral and Craniofacial Anomalies of Fraser Syndrome: Prosthetic Management
Author(s)
Author's Affiliation
Other Contributor(s)
Abstract
Fraser syndrome (FS, MIM 219000) is a rare autosomal disorder characterized by systemic and oro-facial malformation, usually comprising cryptophthalmos, laryngeal malformations, syndactyly, and urogenital defects. We presented a 21-year-old FS case with partial missing teeth seeking aesthetic dental treatment. Clinical examination revealed bilateral cryptophthalmos, extensive syndactyly of hands and feet broad nose with the depressed nasal bridge, and surgically corrected bilateral cleft lip. She presented class III jaw relation and reduced the vertical height of the face. Prosthetic rehabilitation of the patient was done with upper and lower overlay dentures made from acrylic resin (VIPI BLOCK TRILUX®, VIPI Industria, Pirassununga, SP, Brazil) using computer-aided design (CAD) and computer-aided manufacturing (CAM) process. At the follow-up visit, the patient presented improved aesthetics and function. Proper management and rehabilitation of FS patients are challenging, but standard guidelines for oral health management are currently lacking. This article presents a case of Fraser syndrome presenting oral and craniofacial anomalies, and prosthetic rehabilitation was done. We also provided recommendations for the optimal oral health care for the FS patients. Functional adaptation and rehabilitation have significant roles in the various functions, survival, and quality of the life of FS patients. Integrated medical-dental care is needed in such patients with support from family members, friends, and colleagues.