Case Report: Vitamin C combined with multiple micronutrient deficiencies is associated with pulmonary arterial hypertension in children with autistic spectrum disorder
Issued Date
2022-10-20
Resource Type
eISSN
2296861X
Scopus ID
2-s2.0-85141195682
Journal Title
Frontiers in Nutrition
Volume
9
Rights Holder(s)
SCOPUS
Bibliographic Citation
Frontiers in Nutrition Vol.9 (2022)
Suggested Citation
Sakamornchai W., Dumrongwongsiri O., Siwarom S. Case Report: Vitamin C combined with multiple micronutrient deficiencies is associated with pulmonary arterial hypertension in children with autistic spectrum disorder. Frontiers in Nutrition Vol.9 (2022). doi:10.3389/fnut.2022.928026 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/83113
Title
Case Report: Vitamin C combined with multiple micronutrient deficiencies is associated with pulmonary arterial hypertension in children with autistic spectrum disorder
Author(s)
Author's Affiliation
Other Contributor(s)
Abstract
Children with developmental and behavioral problems including autistic spectrum disorders (ASDs) may have inappropriate feeding behaviors, which leads to an increased risk of multiple nutrient deficiencies. Vitamin C deficiency is one of the common nutrient deficiencies reported in children with inappropriate feeding. This case report illustrates two cases of ASD children with a clinical presentation of pulmonary arterial hypertension, a rare presentation of vitamin C deficiency. Vitamin C supplementation, pulmonary vasodilator, and supportive treatment were provided. Patients could recover from the illness and could be discharged from the hospital in a short time. In addition to vitamin C, the patients also had multiple micronutrient deficiencies. Nutrition counseling was given and micronutrient supplement was continued until follow-up. Regular nutrition assessment and counseling among children with ASD are needed to prevent nutrient deficiencies which may lead to life-threatening complications.