Electrochemical detection of creatinine using Au–Ag bimetallic nanoparticles
1
Issued Date
2023-01-01
Resource Type
ISSN
14328488
eISSN
14330768
Scopus ID
2-s2.0-85162716694
Journal Title
Journal of Solid State Electrochemistry
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Solid State Electrochemistry (2023)
Suggested Citation
Nene A., Phanthong C., Surareungchai W., Somasundrum M. Electrochemical detection of creatinine using Au–Ag bimetallic nanoparticles. Journal of Solid State Electrochemistry (2023). doi:10.1007/s10008-023-05571-1 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/87764
Title
Electrochemical detection of creatinine using Au–Ag bimetallic nanoparticles
Author(s)
Other Contributor(s)
Abstract
The adsorption of creatinine has been examined at Au–Ag bimetallic nanoparticles. In phosphate buffer without a supporting electrolyte, both metals were oxidised within a single voltammetric peak. The oxidation peak height was inversely proportional to the creatinine concentration, indicating adsorption of the species onto the particles. The adsorption followed a Langmuir isotherm with a free energy of adsorption estimated at − 14.4 kJ mol−1. The adsorption was found to be selective in the presence of interferents such as glucose, glycine, and urea. Using the decrease in peak height creatinine could be calibrated with an LOD of 0.8 mM (defined as 3.3σ/S where σ is the standard deviation of the blank and S is the calibration gradient) and a sensitivity of 137.0 µA mM−1 (r 2 = 0.998). Recoveries of creatinine in artificial urine were in the range 92.8 to 104.5%.