Detection of hepa titis e virus in deer and monkey in Thailand
Issued Date
2013
Resource Type
Language
eng
Rights
Mahidol University
Suggested Citation
Nathamon Kosoltanapiwat, ณฐมน โกศลธนาภิวัฒน, Pornsawan Leaungwutiwong, พรสวรรค์ เหลืองวุฒิวงษ์, Narin Thippornchai, นรินทร์ ทิพย์พรชัย, Mori, Hirotake, Aongart Mahittikorn, องอาจ มหิทธิกร, Marnoch Yindee, Okabayashi, Tamaki (2013). Detection of hepa titis e virus in deer and monkey in Thailand. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/63359
Title
Detection of hepa titis e virus in deer and monkey in Thailand
Abstract
Hepatitis E virus (HEV) infection in human leads to an acute viral hepatitis that is transmitted via fecaloral
route through consumptions of contaminated water or food. Four genotypes of HEV (HEV-1
to -4) have been described worldwide. HEV-1 and HEV-2 are found in human. HEV-3 and HEV-4
are found in both human and animals such as pig, wild boar and deer, indicating a zoonotic transmission.
There were evidences showed that human got HEV zoonotic infections by contact with contaminated animal
materials or eating contaminated undercooked animal products. In this study, a prevalence of HEV was
surveyed in deer and monkey. Deer feces (n=47) were collected from a forest ground in Kanchanaburi
Province where human and animal areas are superimposed. Monkey feces (n=55) were collected from an area
in Lopburi Province where monkeys live in close contact with human. By semi-nested RT -PCR of 30% fecal
suspension with primers specific to a region in 5’ non-coding region (5’NCR) of HEV genome, 21.3% of deer
and 25.5% of monkey fecal samples were positive for HEV RNA. An incidence of diseases in the animals was
not inspected. However, all feces were normal in their gross appearances. The results suggest that deer and
monkey could be potential reservoirs of HEV, although a possibility of the animals acquired the virus from
human is not ruled out. The risk of HEV contamination from wild animals to human environment such as
water and food also needs to be examined in human habitats.
Description
Joint International Tropical Medicine Meeting 2013: Towards global health: an Asian paradigm of Tropical Medicine 11-13 December 2013 Centara Grand Bangkok Convention Center at Central World, Bangkok, Thailand. Bangkok: Faculty of Tropical Medicine, Mahidol University; 2013. p.163.