Ag/Au-incorporated trimethyl chitosan-shell hybrid particles as reinforcing and antioxidant fillers for trimethyl chitosan hydrogel
Issued Date
2024-08-01
Resource Type
ISSN
01448617
Scopus ID
2-s2.0-85190330504
Journal Title
Carbohydrate Polymers
Volume
337
Rights Holder(s)
SCOPUS
Bibliographic Citation
Carbohydrate Polymers Vol.337 (2024)
Suggested Citation
Lekjinda K., Sunintaboon P., Watthanaphanit A., Tangboriboonrat P., Ubol S. Ag/Au-incorporated trimethyl chitosan-shell hybrid particles as reinforcing and antioxidant fillers for trimethyl chitosan hydrogel. Carbohydrate Polymers Vol.337 (2024). doi:10.1016/j.carbpol.2024.122132 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/98066
Title
Ag/Au-incorporated trimethyl chitosan-shell hybrid particles as reinforcing and antioxidant fillers for trimethyl chitosan hydrogel
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
N,N,N-Trimethyl chitosan (TMC) is a quaternized chitosan with versatile biological features. However, low mechanical strength limits its uses, for example, as hydrogels for tissue engineering applications. This study illustrates a viable synthesis of metal/polymer hybrid, core-shell colloidal particles and their use as reinforcing and antioxidant fillers for TMC hydrogels. The core-shell particles were initially synthesized by surfactant-free emulsion polymerization, induced by a photo-redox initiating system of riboflavin assisted by a 3° amine and 2° alcohol co-initiators. The synthesized core-shell particles were based on two polymeric shells: TMC and chitosan, and two polymeric cores: poly (hydroxypropyl methacrylate) (PHPMA) and poly(2-hydroxy ethyl methacrylate) (PHEMA). The presence of both 3° amine on TMC and 2° alcohol on HPMA monomer enhanced the photopolymerization performance. The TMC-based particles had sizes of 122–154 nm and zeta potentials of 10–35 mV, bringing the colloidal stability in the 4–10 pH range. Furthermore, due to the presence of TMC on the shell layer, the core-shell particles could be used as templates to grow the Ag/Au bimetallic nanoparticles with alloy and core-shell types through a thermal reduction. The prepared hybrid particles were incorporated in TMC hydrogels as a multifunctional filler, improving their mechanical and antioxidant properties.