Aging and Adiposity—Focus on Biological Females at Midlife and Beyond
Issued Date
2024-03-01
Resource Type
ISSN
16616596
eISSN
14220067
Scopus ID
2-s2.0-85187416231
Journal Title
International Journal of Molecular Sciences
Volume
25
Issue
5
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Molecular Sciences Vol.25 No.5 (2024)
Suggested Citation
Rehman A., Lathief S., Charoenngam N., Pal L. Aging and Adiposity—Focus on Biological Females at Midlife and Beyond. International Journal of Molecular Sciences Vol.25 No.5 (2024). doi:10.3390/ijms25052972 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/97653
Title
Aging and Adiposity—Focus on Biological Females at Midlife and Beyond
Author(s)
Corresponding Author(s)
Other Contributor(s)
Abstract
Menopause is a physiological phase of life of aging women, and more than 1 billion women worldwide will be in menopause by 2025. The processes of global senescence parallel stages of reproductive aging and occur alongside aging-related changes in the body. Alterations in the endocrine pathways accompany and often predate the physiologic changes of aging, and interactions of these processes are increasingly being recognized as contributory to the progression of senescence. Our goal for this review is to examine, in aging women, the complex interplay between the endocrinology of menopause transition and post-menopause, and the metabolic transition, the hallmark being an increasing tendency towards central adiposity that begins in tandem with reproductive aging and is often exacerbated post menopause. For the purpose of this review, our choice of the terms ‘female’ and ‘woman’ refer to genetic females.