Effects of Caffeine on Kidney Stone Disease and Renal Cancer
5
Issued Date
2025-05-23
Resource Type
ISSN
23980656
eISSN
23980664
Scopus ID
2-s2.0-105040575445
Journal Title
Food Chemistry Function and Analysis
Volume
45
Start Page
264
End Page
272
Rights Holder(s)
SCOPUS
Bibliographic Citation
Food Chemistry Function and Analysis Vol.45 (2025) , 264-272
Suggested Citation
Peerapen P., Thongboonkerd V. Effects of Caffeine on Kidney Stone Disease and Renal Cancer. Food Chemistry Function and Analysis Vol.45 (2025) , 264-272. 272. doi:10.1039/9781839166853-00264 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/117220
Title
Effects of Caffeine on Kidney Stone Disease and Renal Cancer
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Abstract
Caffeine is a natural xanthine alkaloid commonly found in coffee beans, cocoa beans, and tea leaves. It acts as a non-selective adenosine receptor antagonist and can block adenosine receptors expressed on renal tubular epithelial cells, leading to diuresis and natriuresis. Caffeine has long been known to have beneficial effects on human health, as it can reduce risks of many diseases. Several lines of recent evidence have shown the protective roles of coffee and caffeine consumption in kidney stone disease and renal cancer. This chapter thus provides an overview of the physiological roles of caffeine in kidney functions and summarizes the previous and recent data on the roles of coffee and caffeine consumption in kidney stone disease and renal cancer.