Mechanisms and Physiological Roles of Polymorphisms in Gestational Diabetes Mellitus
2
Issued Date
2024-02-07
Resource Type
eISSN
14220067
Scopus ID
2-s2.0-85186264883
Pubmed ID
38396716
Journal Title
International journal of molecular sciences
Volume
25
Issue
4
Rights Holder(s)
SCOPUS
Bibliographic Citation
International journal of molecular sciences Vol.25 No.4 (2024)
Suggested Citation
Suthon S., Tangjittipokin W. Mechanisms and Physiological Roles of Polymorphisms in Gestational Diabetes Mellitus. International journal of molecular sciences Vol.25 No.4 (2024). doi:10.3390/ijms25042039 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/97508
Title
Mechanisms and Physiological Roles of Polymorphisms in Gestational Diabetes Mellitus
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Abstract
Gestational diabetes mellitus (GDM) is a significant pregnancy complication linked to perinatal complications and an elevated risk of future metabolic disorders for both mothers and their children. GDM is diagnosed when women without prior diabetes develop chronic hyperglycemia due to β-cell dysfunction during gestation. Global research focuses on the association between GDM and single nucleotide polymorphisms (SNPs) and aims to enhance our understanding of GDM's pathogenesis, predict its risk, and guide patient management. This review offers a summary of various SNPs linked to a heightened risk of GDM and explores their biological mechanisms within the tissues implicated in the development of the condition.