Inflammatory auto-immune diseases of the intestine and their management by natural bioactive compounds
1
Issued Date
2022-07-01
Resource Type
ISSN
07533322
eISSN
19506007
Scopus ID
2-s2.0-85131429713
Pubmed ID
35644116
Journal Title
Biomedicine and Pharmacotherapy
Volume
151
Rights Holder(s)
SCOPUS
Bibliographic Citation
Biomedicine and Pharmacotherapy Vol.151 (2022)
Suggested Citation
El Menyiy N., El Allam A., Aboulaghras S., Jaouadi I., Bakrim S., El Omari N., Shariati M.A., Miftakhutdinov A., Wilairatana P., Mubarak M.S., Bouyahya A. Inflammatory auto-immune diseases of the intestine and their management by natural bioactive compounds. Biomedicine and Pharmacotherapy Vol.151 (2022). doi:10.1016/j.biopha.2022.113158 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/86849
Title
Inflammatory auto-immune diseases of the intestine and their management by natural bioactive compounds
Author's Affiliation
Faculty of Tropical Medicine, Mahidol University
South Ural State Agrarian University
Moscow State University of Technologies and Management
Faculté de Médecine et de Pharmacie de Rabat
The University of Jordan
Faculty of Science, Ibn Tofail University
Mohammed V University in Rabat
Université Ibn Zohr
Faculté des Sciences Rabat
National Agency of Medicinal and Aromatic Plants
South Ural State Agrarian University
Moscow State University of Technologies and Management
Faculté de Médecine et de Pharmacie de Rabat
The University of Jordan
Faculty of Science, Ibn Tofail University
Mohammed V University in Rabat
Université Ibn Zohr
Faculté des Sciences Rabat
National Agency of Medicinal and Aromatic Plants
Other Contributor(s)
Abstract
Autoimmune diseases are caused by the overactivity of the immune system towards self-constituents. Risk factors of autoimmune diseases are multiple and include genetic, epigenetic, environmental, and psychological. Autoimmune chronic inflammatory bowel diseases, including celiac and inflammatory diseases (Crohn's disease and ulcerative colitis), constitute a significant health problem worldwide. Besides the complexity of the symptoms of these diseases, their treatments have only been palliative. Numerous investigations showed that natural phytochemicals could be promising strategies to fight against these autoimmune diseases. In this respect, plant-derived natural compounds such as flavonoids, phenolic acids, and terpenoids exhibited significant effects against three autoimmune diseases affecting the intestine, particularly bowel diseases. This review focuses on the role of natural compounds obtained from medicinal plants in modulating inflammatory auto-immune diseases of the intestine. It covers the most recent literature related to the effect of these natural compounds in the treatment and prevention of auto-immune diseases of the intestine.