Drimane-Type Sesquiterpenoids Derived from the Tropical Basidiomycetes Perenniporia centrali-africana and Cerrena sp. nov
Issued Date
2022-09-01
Resource Type
eISSN
14203049
Scopus ID
2-s2.0-85138947618
Journal Title
Molecules
Volume
27
Issue
18
Rights Holder(s)
SCOPUS
Bibliographic Citation
Molecules Vol.27 No.18 (2022)
Suggested Citation
Pathompong P., Pfütze S., Surup F., Boonpratuang T., Choeyklin R., Matasyoh J.C., Decock C., Stadler M., Boonchird C. Drimane-Type Sesquiterpenoids Derived from the Tropical Basidiomycetes Perenniporia centrali-africana and Cerrena sp. nov. Molecules Vol.27 No.18 (2022). doi:10.3390/molecules27185968 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/84162
Title
Drimane-Type Sesquiterpenoids Derived from the Tropical Basidiomycetes Perenniporia centrali-africana and Cerrena sp. nov
Other Contributor(s)
Abstract
Five new drimane-type sesquiterpenoids were isolated from cultures of the tropical basidiomycetes, Perenniporia centrali-africana (originating from Kenya) and Cerrena sp. nov. (originating from Thailand). A new pereniporin A derivative (1), a new drimane-type sesquiterpene lactam (2), and the new 6,7-Dehydro-isodrimenediol (3) were isolated from P. centrali-africana. In parallel, the two new drimane-type sesquiterpene lactams 5 and 6 were isolated together with known isodrimenediol (4) from Cerrena sp. This is the first report of drimane-type sesquiterpene lactams from basidiomycetes. The structures were elucidated based on 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data, in combination with high-resolution electrospray mass spectrometric (HR-ESIMS) data. The compounds were devoid of significant antimicrobial and cytotoxic activities.