Nomogram of the anterior cerebral artery doppler indices at 11–13+6 weeks of gestation
Issued Date
2025-12-01
Resource Type
eISSN
14712393
Scopus ID
2-s2.0-105013268654
Journal Title
BMC Pregnancy and Childbirth
Volume
25
Issue
1
Rights Holder(s)
SCOPUS
Bibliographic Citation
BMC Pregnancy and Childbirth Vol.25 No.1 (2025)
Suggested Citation
Wanasitchaiwat O., Surasereewong S., Supapueng O., Panchalee T., Moungmaithong S. Nomogram of the anterior cerebral artery doppler indices at 11–13+6 weeks of gestation. BMC Pregnancy and Childbirth Vol.25 No.1 (2025). doi:10.1186/s12884-025-07993-3 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/111804
Title
Nomogram of the anterior cerebral artery doppler indices at 11–13+6 weeks of gestation
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Abstract
Objective: To establish nomograms of anterior cerebral artery (ACA) Doppler indices during 11–13<sup>+6</sup> weeks of gestation. Methods: A descriptive cross-sectional study was conducted on low-risk singleton pregnancies with healthy fetuses. The ACA Doppler spectral waveforms were obtained using transabdominal Doppler sonography, in the same plane as the nuchal translucency measurement. The normative data were analyzed and constructed for the 5th, 10th, 50th, 90th, and 95th percentiles of ACA Doppler indices during 11–13<sup>+6</sup> weeks of gestation. Results: A total of 216 low-risk singleton pregnancies with healthy fetuses were enrolled in this study; 12 pregnancies were excluded due to duplicating data, affected fetuses by Thalassemia disease, abortion, fetal structural anomalies, fetal growth abnormalities, or uninformed or unrevealed underlying medical conditions. Anterior cerebral artery Doppler was measured, and the nomograms for ACA Doppler indices (ACA-PI, ACA-RI, and ACA-PSV), including the 5th, 10th, 50th, 90th, and 95th percentiles during the gestational period of 11–13<sup>+6</sup> weeks, were established. The range of 5th – 95th percentile of ACA-PI, ACA-RI and ACA-PSV during 11 weeks of gestation were 1.15–1.86, 0.65–0.82 and 6.76–14.40, respectively, during 12 weeks of gestation were 1.22–1.90, 0.65–0.88 and 7.09–15.03, respectively and during 13 weeks of gestation were 1.26–1.82, 0.67–0.84 and 7.69–17.40, respectively. Conclusion: During 11–13<sup>+6</sup> weeks of gestation, the ACA-PI and ACA-RI values remained relatively constant, while PSV values gradually increased with gestation.