Isolated Adrenal Abscess Due to Melioidosis
2
Issued Date
2025-08-06
Resource Type
eISSN
14761645
Scopus ID
2-s2.0-105013157407
Pubmed ID
40460819
Journal Title
American Journal of Tropical Medicine and Hygiene
Volume
113
Issue
2
Start Page
395
End Page
398
Rights Holder(s)
SCOPUS
Bibliographic Citation
American Journal of Tropical Medicine and Hygiene Vol.113 No.2 (2025) , 395-398
Suggested Citation
Teerajetgul S., Jantarapootirat M., Traiwanatham S., Kirdlarp S., Sriphrapradang C. Isolated Adrenal Abscess Due to Melioidosis. American Journal of Tropical Medicine and Hygiene Vol.113 No.2 (2025) , 395-398. 398. doi:10.4269/ajtmh.25-0154 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/111741
Title
Isolated Adrenal Abscess Due to Melioidosis
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
Melioidosis is a potentially life-threatening infectious disease that is endemic to tropical regions such as Southeast Asia and northern Australia. We report a case of melioidosis presenting as an isolated right adrenal abscess in an elderly woman with diabetes mellitus. The patient presented with fever and nonspecific abdominal pain, which was initially misdiagnosed as a urinary tract infection. Blood cultures identified Burkholderia pseudomallei, prompting further investigation using computed tomography, which revealed a multiloculated abscess in the right adrenal gland. Management included an intensive phase of intravenous ceftazidime combined with trimethoprim-sulfamethoxazole, followed by an eradication phase with oral trimethoprim-sulfamethoxazole. The patient showed clinical and radiologic improvement with antibiotic therapy alone. No clinical or biochemical evidence of adrenal insufficiency was observed. This case highlights the diagnostic and therapeutic challenges of adrenal melioidosis, emphasizing the need for early recognition, tailored antimicrobial therapy, and vigilant follow-up to prevent relapse and manage complications such as adrenal insufficiency.