Allogeneic adipose MSCs and autologous PRP for chronic non-healing wound in a cat
Issued Date
2025-01-01
Resource Type
ISSN
03758427
Scopus ID
2-s2.0-105004033178
Journal Title
Veterinarni Medicina
Volume
70
Issue
4
Start Page
143
End Page
149
Rights Holder(s)
SCOPUS
Bibliographic Citation
Veterinarni Medicina Vol.70 No.4 (2025) , 143-149
Suggested Citation
Suwan N., Jenjittikul S., Tiratrakoonseree R., Jiradanaipat C., Teerawongsuwan S., Phathomrapeepong W., Phanwanich W., Rungsiwiwut R. Allogeneic adipose MSCs and autologous PRP for chronic non-healing wound in a cat. Veterinarni Medicina Vol.70 No.4 (2025) , 143-149. 149. doi:10.17221/93/2024-VETMED Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/109986
Title
Allogeneic adipose MSCs and autologous PRP for chronic non-healing wound in a cat
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
Management of chronic non-healing wounds in cats requires a comprehensive approach. This report describes the treatment of a severe open skin wound on the skull using a combined approach involving allogeneic adipose-derived mesenchymal stem cells (MSCs) and autologous platelet-rich plasma (PRP). A 12-year-old neutered male mixed-breed domestic cat presented with a non-healing chronic wound on the skull. The wound extended from the orbital to the occipital area and from the left to the right temporal region. Laboratory test results were positive for feline immunodeficiency virus and impaired kidney function. Sensitivity tests revealed resistance to several antibiotics. Due to limited skin reconstruction options, MSCs were administered subcutaneously at the wound edge once a month for three months. PRP was collected one month after the initial MSC administration and injected at the wound edge monthly between MSC treatments. The wound diameter was measured daily during saline cleaning. The cat received protein-supplemented food daily. Wound healing was observed two weeks after the MSC administration, gradually decreasing in size and closing completely within 5 months. This case demonstrates the successful application of MSCs and PRP for treating chronic wounds in cats.