Improvement in the Youthfulness of Facial Skin after a Single Treatment with Platelet Rich Plasma
Issued Date
2024-01-01
Resource Type
eISSN
22288082
Scopus ID
2-s2.0-85208242707
Journal Title
Siriraj Medical Journal
Volume
76
Issue
11
Start Page
781
End Page
788
Rights Holder(s)
SCOPUS
Bibliographic Citation
Siriraj Medical Journal Vol.76 No.11 (2024) , 781-788
Suggested Citation
Akaranuchat N., Kongkunnavat N. Improvement in the Youthfulness of Facial Skin after a Single Treatment with Platelet Rich Plasma. Siriraj Medical Journal Vol.76 No.11 (2024) , 781-788. 788. doi:10.33192/smj.v76i11.270077 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/101983
Title
Improvement in the Youthfulness of Facial Skin after a Single Treatment with Platelet Rich Plasma
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Abstract
Objective: Platelet rich plasma (PRP) is an autologous substance widely used to stimulate dermal collagen synthesis. This study aimed to investigate the efficacy of a single PRP treatment for facial rejuvenation. Materials and Methods: This study was conducted at the Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand from August 2020 to March 2021. Enrolled patients underwent a single intradermal injection treatment of 0.1 mL PRP at 30 locations on the face. Outcomes were assessed at 1, 2, and 4 weeks post-intervention using the patient-perceived age visual analog scale (VAS), FACE-Q assessment, and elasticity index (EI) with a Cutometer. Results: Forty Thai patients with an average age of 36.4 years, Fitzpatrick skin type 3–4 were enrolled. The mean Patient-perceived Age VAS significantly decreased one month after treatment (-2.71±2.42, p<0.001). FACE-Q satisfaction with facial skin was 74.29±14.49, and satisfaction with the outcome was 73.41±16.26 (scale 0-100). The PRP significantly affected skin EI, with the peak improvement observed at 1–2 weeks post-injection, predominantly at the cheek, crow’s feet, and perioral area (all p<0.05). All patients had an overall improvement in satisfaction scores throughout the study. Conclusion: A single treatment of PRP injection resulted in overall satisfaction in facial skin rejuvenation as measured by patient-perceived age VAS and FACE-Q assessment. The PRP showed positive outcomes in EI with peak performance at 1–2 weeks post-treatment.