NUMERICAL SIMULATION TO INVESTIGATE THE BEHAVIOR OF THE BONE REMODELING PROCESS IN HEALTHY AND TUMOROUS BONE USING FRACTIONAL DERIVATIVES WITH TIME-DELAY
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Issued Date
2025-11-01
Resource Type
ISSN
21852766
Scopus ID
2-s2.0-105017183079
Journal Title
Icic Express Letters Part B Applications
Volume
16
Issue
11
Start Page
1211
End Page
1218
Rights Holder(s)
SCOPUS
Bibliographic Citation
Icic Express Letters Part B Applications Vol.16 No.11 (2025) , 1211-1218
Suggested Citation
Janngarm C., Khajohnsaksumeth N. NUMERICAL SIMULATION TO INVESTIGATE THE BEHAVIOR OF THE BONE REMODELING PROCESS IN HEALTHY AND TUMOROUS BONE USING FRACTIONAL DERIVATIVES WITH TIME-DELAY. Icic Express Letters Part B Applications Vol.16 No.11 (2025) , 1211-1218. 1218. doi:10.24507/icicelb.16.11.1211 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/112421
Title
NUMERICAL SIMULATION TO INVESTIGATE THE BEHAVIOR OF THE BONE REMODELING PROCESS IN HEALTHY AND TUMOROUS BONE USING FRACTIONAL DERIVATIVES WITH TIME-DELAY
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Abstract
Bone remodeling is the intricate process responsible for the repairing of old and damaged bone within the human body. Nonetheless, this cycle can be disrupted by various factors, leading to bone diseases such as osteoporosis. In this research, we investigate bone remodeling in both healthy and tumorous bone tissues, using the fractional derivatives technique and time delay method in our model. We also provide a numerical solution of the influence of various parameters on this cycle. The results present that both the order of the fractional derivative and the time delay significantly impact the model's behavior. Specifically, higher orders of the fractional derivative and the greater amount of time delays contribute to a more rapid progression of the modeled dynamics compared to the original model.
