Marine life as a source for breast cancer treatment: A comprehensive review
Issued Date
2023-03-01
Resource Type
ISSN
07533322
eISSN
19506007
Scopus ID
2-s2.0-85146073622
Pubmed ID
36634590
Journal Title
Biomedicine and Pharmacotherapy
Volume
159
Rights Holder(s)
SCOPUS
Bibliographic Citation
Biomedicine and Pharmacotherapy Vol.159 (2023)
Suggested Citation
Hussain A., Bourguet-Kondracki M.L., Majeed M., Ibrahim M., Imran M., Yang X.W., Ahmed I., Altaf A.A., Khalil A.A., Rauf A., Wilairatana P., Hemeg H.A., Ullah R., Green I.R., Ali I., Shah S.T.A., Hussain H. Marine life as a source for breast cancer treatment: A comprehensive review. Biomedicine and Pharmacotherapy Vol.159 (2023). doi:10.1016/j.biopha.2022.114165 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/82205
Title
Marine life as a source for breast cancer treatment: A comprehensive review
Author's Affiliation
Faculty of Tropical Medicine, Mahidol University
University of Okara
Sukkur IBA University
University of Swabi
Department of Chemical Engineering and Biotechnology
Ministry of Land and Resources P.R.C.
Karakoram International University
Government College University Faisalabad
University of Lahore
Museum National d'Histoire Naturelle
King Khalid University
Leibniz Institut fur Pflanzenbiochemie
Taibah University
College of Pharmacy
Stellenbosch University
University of Okara
Sukkur IBA University
University of Swabi
Department of Chemical Engineering and Biotechnology
Ministry of Land and Resources P.R.C.
Karakoram International University
Government College University Faisalabad
University of Lahore
Museum National d'Histoire Naturelle
King Khalid University
Leibniz Institut fur Pflanzenbiochemie
Taibah University
College of Pharmacy
Stellenbosch University
Other Contributor(s)
Abstract
Breast cancer, one of the most significant tumors among all cancer cells, still has deficiencies for effective treatment. Moreover, substitute treatments employing natural products as bioactive metabolites has been seriously considered. The source of bioactive metabolites are not only the most numerous but also represent the richest source. A unique source is from the oceans or marine species which demonstrated intriguing chemical and biological diversity which represents an astonishing reserve for discovering novel anticancer drugs. Notably, marine sponges produce the largest amount of diverse bioactive peptides, alkaloids, terpenoids, polyketides along with many secondary metabolites whose potential is mostly therapeutic. In this review, our main focus is on the marine derived secondary metabolites which demonstrated cytotoxic effects towards numerous breast cancer cells and have been isolated from the marine sources such as marine sponges, cyanobacteria, fungi, algae, tunicates, actinomycetes, ascidians, and other sources of marine organisms.