Frequency of antimicrobial-resistant bloodstream infections in 111 hospitals in Thailand, 2022
Issued Date
2024-10-01
Resource Type
ISSN
01634453
eISSN
15322742
Scopus ID
2-s2.0-85201764027
Pubmed ID
39173918
Journal Title
Journal of Infection
Volume
89
Issue
4
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Infection Vol.89 No.4 (2024)
Suggested Citation
Tuamsuwan K., Chamawan P., Boonyarit P., Srisuphan V., Klaytong P., Rangsiwutisak C., Wannapinij P., Fongthong T., Stelling J., Turner P., Limmathurotsakul D. Frequency of antimicrobial-resistant bloodstream infections in 111 hospitals in Thailand, 2022. Journal of Infection Vol.89 No.4 (2024). doi:10.1016/j.jinf.2024.106249 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/100686
Title
Frequency of antimicrobial-resistant bloodstream infections in 111 hospitals in Thailand, 2022
Corresponding Author(s)
Other Contributor(s)
Abstract
Objectives: To evaluate the frequency of antimicrobial-resistant bloodstream infections (AMR BSI) in Thailand. Methods: We analyzed data from 2022, generated by 111 public hospitals in health regions 1 to 12, using the AutoMated tool for Antimicrobial resistance Surveillance System (AMASS), and submitted to the Ministry of Public Health, Thailand. Multilevel Poisson regression models were used. Results: The most common cause of community-origin AMR BSI was third-generation cephalosporin-resistant Escherichia coli (3GCREC, 65.6%; 5101/7773 patients) and of hospital-origin AMR BSI was carbapenem-resistant Acinetobacter baumannii (CRAB, 51.2%, 4968/9747 patients). The percentage of patients tested for BSI was negatively associated with the frequency of community-origin 3GCREC BSI and hospital-origin CRAB BSI (per 100,000 tested patients). Hospitals in health regions 4 (lower central region) had the highest frequency of community-origin 3GCREC BSI (adjusted incidence rate ratio, 2.06; 95% confidence interval: 1.52–2.97). Health regions were not associated with the frequency of hospital-origin CRAB BSI, and between-hospital variation was high, even adjusting for hospital level and size. Conclusion: The high between-hospital variation of hospital-origin CRAB BSI suggests the importance of hospital-specific factors. Our approach and findings highlight health regions and hospitals where actions against AMR infection, including antimicrobial stewardship and infection control, should be prioritized.