Medication errors in emergency departments: a systematic review and meta-analysis of prevalence and severity
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Issued Date
2024-01-01
Resource Type
ISSN
22107703
eISSN
22107711
Scopus ID
2-s2.0-85192812773
Journal Title
International Journal of Clinical Pharmacy
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Clinical Pharmacy (2024)
Suggested Citation
Nguyen P.T.L., Phan T.A.T., Vo V.B.N., Ngo N.T.N., Nguyen H.T., Phung T.L., Kieu M.T.T., Nguyen T.H., Duong K.N.C. Medication errors in emergency departments: a systematic review and meta-analysis of prevalence and severity. International Journal of Clinical Pharmacy (2024). doi:10.1007/s11096-024-01742-w Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/98420
Title
Medication errors in emergency departments: a systematic review and meta-analysis of prevalence and severity
Corresponding Author(s)
Other Contributor(s)
Abstract
Background: Medication errors significantly compromise patient safety in emergency departments. Although previous studies have investigated the prevalence of these errors in this setting, results have varied widely. Aim: The aim was to report pooled data on the prevalence and severity of medication errors in emergency departments, as well as the proportion of patients affected by these errors. Method: Systematic searches were conducted in Embase, PubMed, and the Cochrane Library from database inception until June 2023. Studies provided numerical data on medication errors within emergency departments were eligible for inclusion. Random-effects meta-analysis was employed to pool the prevalence of medication errors, the proportion of patients experiencing these errors, and the error severity levels. Heterogeneity among studies was assessed using the I2 statistic and Cochran’s Q test. Results: Twenty-four studies met the inclusion criteria. The meta-analysis gave a pooled prevalence of medication errors in emergency departments of 22.6% (95% Confidence Interval [CI] 19.2–25.9%, I2 = 99.9%, p < 0.001). The estimated proportion of patients experiencing medication errors was 36.3% (95% CI 28.3–44.3%, I2 = 99.8%, p < 0.001). Of these errors, 42.6% (95% CI 5.0–80.1%) were potentially harmful but not life-threatening, while no-harm errors accounted for 57.3% (95% CI 14.1–100.0%). Conclusion: The prevalence of medication errors, particularly those potentially harmful, underscores potential safety issues in emergency departments. It is imperative to develop and implement effective interventions aimed at reducing medication errors and enhancing patient safety in this setting.