Effectiveness of a cognitive behavioral therapy-integrated, hospital-based program for prediabetes: a matched cohort study
2
Issued Date
2024-12-01
Resource Type
eISSN
20452322
Scopus ID
2-s2.0-85189773800
Journal Title
Scientific Reports
Volume
14
Issue
1
Rights Holder(s)
SCOPUS
Bibliographic Citation
Scientific Reports Vol.14 No.1 (2024)
Suggested Citation
Washirasaksiri C., Pakornnipat W., Ariyakunaphan P., Kositamongkol C., Polmanee C., Preechasuk L., Jaiborisuttigull N., Sitasuwan T., Tinmanee R., Pramyothin P., Srivanichakorn W. Effectiveness of a cognitive behavioral therapy-integrated, hospital-based program for prediabetes: a matched cohort study. Scientific Reports Vol.14 No.1 (2024). doi:10.1038/s41598-024-58739-8 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/97978
Title
Effectiveness of a cognitive behavioral therapy-integrated, hospital-based program for prediabetes: a matched cohort study
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
Intensive lifestyle interventions are effective in preventing T2DM, but evidence is lacking for high cardiometabolic individuals in hospital settings. We evaluated a hospital-based, diabetes prevention program integrating cognitive behavioral therapy (CBT) for individuals with prediabetes. This matched cohort assessed individuals with prediabetes receiving the prevention program, which were matched 1:1 with those receiving standard care. The year-long program included five in-person sessions and several online sessions covering prediabetes self-management, dietary and behavioral interventions. Kaplan–Meier and Cox regression models estimated the 60-month T2DM incidence rate. Of 192 patients, 190 joined the prevention program, while 190 out of 10,260 individuals were in the standard-care group. Both groups had similar baseline characteristics (mean age 58.9 ± 10.2 years, FPG 102.3 ± 8.2 mg/dL, HbA1c 5.9 ± 0.3%, BMI 26.2 kg/m2, metabolic syndrome 75%, and ASCVD 6.3%). After 12 months, the intervention group only showed significant decreases in FPG, HbA1c, and triglyceride levels and weight. At 60 months, the T2DM incidence rate was 1.7 (95% CI 0.9–2.8) in the intervention group and 3.5 (2.4–4.9) in the standard-care group. After adjusting for variables, the intervention group had a 0.46 times lower risk of developing diabetes. Therefore, healthcare providers should actively promote CBT-integrated, hospital-based diabetes prevention programs to halve diabetes progression.