Seroprevalence study of arboviruses in Bangphae district, Ratchaburi province, Thailand
1
Issued Date
2022
Copyright Date
2022
Resource Type
Language
eng
File Type
application/pdf
No. of Pages/File Size
viii, 61 leaves : ill.
Access Rights
open access
Rights
ผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้า
Rights Holder(s)
Mahidol University
Bibliographic Citation
Thematic Paper (M.C.T.M. (Tropical Pediatrics))--Mahidol University, 2022)
Suggested Citation
Chakma, Ruba, 1982- Seroprevalence study of arboviruses in Bangphae district, Ratchaburi province, Thailand. Thematic Paper (M.C.T.M. (Tropical Pediatrics))--Mahidol University, 2022). Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/113818
Title
Seroprevalence study of arboviruses in Bangphae district, Ratchaburi province, Thailand
Author(s)
Abstract
In recent decades, arboviruses have become a global threat because of their increasing incidence and rapidly expanding geographical range. Although most arboviral diseases are mild, severe infections may lead to death. To better understand the disease's actual burden and the nature of spreading with information about past exposure, it is essential to perform a seroprevalence study. The objective of this study was to find out the prevalence of previous exposure to three major arboviruses: Dengue virus (DENV), Chikungunya virus (CHIKV), and Zika virus (ZIKV), in the population of Bang Phae district, Ratchaburi province, Thailand. This retrospective cross-sectional study used stored serum samples from a previous dengue virus seroprevalence study in Bang Phae district, Ratchaburi province, Thailand, conducted from 2012 to 2015, to determine the seroprevalence and transmission dynamics of DENV, CHIKV, and ZIKV. Four hundred samples, equally distributed by sex and into five age groups from seven subdistricts, were randomly selected for this seroprevalence study. The data were analyzed using SPSS (version 18.0) and Microsoft Excel. The highest seroprevalence was for DENV, followed by ZIKV and CHIKV, at 84.3%, 58.0%, and 22.5%, respectively. The intersection of all three viruses was 16%. This was the first report about the co-circulation of three major arboviruses in the Bang Phae district. From this study, researchers and physicians will get a clear picture and understanding of the co-circulation of these three major arboviruses. The DPP ZCD IgM/IgG CHEMBIO diagnostic system could also be improved according to this study's results. Further study may be required in other endemic areas to understand the actual scenario and disease burdens of arboviruses and their spreading nature to control the disease.
Degree Name
Master of Clinical Tropical Medicine
Degree Level
Master's degree
Degree Department
Faculty of Tropical Medicine
Degree Discipline
Tropical Pediatrics
Degree Grantor(s)
Mahidol University