Furanone, morpholinone and tetrahydrofuran derivatives from the marine-derived fungus Talaromyces sp. PSU-MF07
Issued Date
2022-01-01
Resource Type
ISSN
14786419
eISSN
14786427
Scopus ID
2-s2.0-85131167294
Pubmed ID
35609143
Journal Title
Natural Product Research
Rights Holder(s)
SCOPUS
Bibliographic Citation
Natural Product Research (2022)
Suggested Citation
Nuansri S., Rukachaisirikul V., Muanprasat C., Phongpaichit S., Preedanon S., Sakayaroj J. Furanone, morpholinone and tetrahydrofuran derivatives from the marine-derived fungus Talaromyces sp. PSU-MF07. Natural Product Research (2022). doi:10.1080/14786419.2022.2079124 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/83378
Title
Furanone, morpholinone and tetrahydrofuran derivatives from the marine-derived fungus Talaromyces sp. PSU-MF07
Other Contributor(s)
Abstract
Three new compounds including one furanone, one morpholinone and one tetrahydrofuran together with three known compounds were isolated from the broth extract of the marine-derived fungus Talaromyces sp. PSU-MF07. The structures of the isolated compounds were determined on the basis of spectroscopic methods. The relative configuration was assigned using NOEDIFF data whereas the absolute configurations were established by Mosher’s method, specific rotations and electronic circular dichroism (ECD) data. Some isolated compounds were tested for antimicrobial activity. Only known penioxalicin exhibited weak antibacterial activity against methicillin-resistant Staphylococcus aureus SK1 with an MIC value of 200 µg/mL.