Pitfalls in gut single-cell eukaryote research
Issued Date
2025-01-01
Resource Type
ISSN
14714922
eISSN
14715007
Scopus ID
2-s2.0-85215102441
Journal Title
Trends in Parasitology
Rights Holder(s)
SCOPUS
Bibliographic Citation
Trends in Parasitology (2025)
Suggested Citation
Tito Tadeo R.Y., Stensvold C.R. Pitfalls in gut single-cell eukaryote research. Trends in Parasitology (2025). doi:10.1016/j.pt.2024.12.011 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/102874
Title
Pitfalls in gut single-cell eukaryote research
Author(s)
Corresponding Author(s)
Other Contributor(s)
Abstract
Gut single-celled eukaryotes (GSCEs) are found in billions of people worldwide, but we still know little about their functions and relationships in human gut ecology. Lately, retrospective analysis of bacterial data obtained by next-generation sequencing (NGS) methods has been used to identify links between GSCEs, gut bacteria, host metabolism, and host phenotypical traits, suggesting possible direct or indirect associations to favorable gut microbiome features and other health parameters. Here, we highlight some of the pitfalls related to the research strategy typically used so far and propose action points that could pave the way for a more accurate understanding of GSCEs in human health and disease.