Liver disease trends in the Asia-Pacific region for the next 50 years
Issued Date
2025-07-01
Resource Type
ISSN
22872728
eISSN
2287285X
Scopus ID
2-s2.0-105010629749
Pubmed ID
40037692
Journal Title
Clinical and Molecular Hepatology
Volume
31
Issue
3
Start Page
671
End Page
684
Rights Holder(s)
SCOPUS
Bibliographic Citation
Clinical and Molecular Hepatology Vol.31 No.3 (2025) , 671-684
Suggested Citation
Shiina S., Maikhuu J., Deng Q., Batsaikhan T., Canseco L.M., Tobari M., Maruyama H., Nagamatsu H., Alcantara-Payawal D., Gani R., Huang Y.H., Tanwandee T., Galati G., Kim Y.J. Liver disease trends in the Asia-Pacific region for the next 50 years. Clinical and Molecular Hepatology Vol.31 No.3 (2025) , 671-684. 684. doi:10.3350/cmh.2025.0043 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/111317
Title
Liver disease trends in the Asia-Pacific region for the next 50 years
Author's Affiliation
Seoul National University College of Medicine
Taipei Veterans General Hospital
Renmin Hospital of Wuhan University
Juntendo University
Siriraj Hospital
Università Campus Bio-Medico di Roma
Universitas Indonesia, RSUPN Dr. Cipto Mangunkusumo
National Cancer Center of Mongolia
De Los Santos Medical Center
Second State Central Hospital
Fatima University Medical Center
Taipei Veterans General Hospital
Renmin Hospital of Wuhan University
Juntendo University
Siriraj Hospital
Università Campus Bio-Medico di Roma
Universitas Indonesia, RSUPN Dr. Cipto Mangunkusumo
National Cancer Center of Mongolia
De Los Santos Medical Center
Second State Central Hospital
Fatima University Medical Center
Corresponding Author(s)
Other Contributor(s)
Abstract
Liver disease has emerged as a critical and escalating public health concern worldwide, with the Asia-Pacific region at the forefront of this challenge due to its vast population and diverse socioeconomic landscape. Over the coming five decades, this region will experience profound changes in liver disease patterns, shaped by rapid urbanization, lifestyle modifications, advancements in medical technologies, and evolving public health strategies. This article of-fers an in-depth analysis of six transformative areas defining the trajectory of liver disease in the region. First, it high-lights the alarming rise of metabolic dysfunction-associated fatty liver disease and metabolic dysfunction-associated steatohepatitis, diseases driven by modern lifestyle factors and inherent metabolic susceptibilities. Concurrently, it celebrates the declining burden of viral hepatitis, underscoring the success of sustained public health interventions. However, new challenges are emerging, such as the growing impact of environmental and occupational exposures on liver health. Breakthroughs in genomic and epigenetic research promise to advance precision medicine, offer-ing targeted therapeutic solutions. Additionally, the integration of artificial intelligence, big data, and telemedicine is poised to revolutionize liver disease management, improving accessibility and personalized care. Finally, the article emphasizes the critical role of robust health policies, preventive strategies, and cross-border collaboration in shaping a healthier future. By synthesizing these insights, the study aims to guide innovative and effective responses to the evolving liver disease landscape in the Asia-Pacific region. (Clin Mol Hepatol 2025;31:671-684).