Recent advancements of nanoparticles application in cancer and neurodegenerative disorders: At a glance
Issued Date
2022-09-01
Resource Type
ISSN
07533322
eISSN
19506007
Scopus ID
2-s2.0-85132228450
Pubmed ID
35717779
Journal Title
Biomedicine and Pharmacotherapy
Volume
153
Rights Holder(s)
SCOPUS
Bibliographic Citation
Biomedicine and Pharmacotherapy Vol.153 (2022)
Suggested Citation
Rahman M.M., Islam M.R., Akash S., Harun-Or-Rashid M., Ray T.K., Rahaman M.S., Islam M., Anika F., Hosain M.K., Aovi F.I., Hemeg H.A., Rauf A., Wilairatana P. Recent advancements of nanoparticles application in cancer and neurodegenerative disorders: At a glance. Biomedicine and Pharmacotherapy Vol.153 (2022). doi:10.1016/j.biopha.2022.113305 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/86839
Title
Recent advancements of nanoparticles application in cancer and neurodegenerative disorders: At a glance
Other Contributor(s)
Abstract
Nanoscale engineering is one of the innovative approaches to heal multitudes of ailments, such as varieties of malignancies, neurological problems, and infectious illnesses. Therapeutics for neurodegenerative diseases (NDs) may be modified in aspect because of their ability to stimulate physiological response while limiting negative consequences by interfacing and activating possible targets. Nanomaterials have been extensively studied and employed for cancerous therapeutic strategies since nanomaterials potentially play a significant role in medical transportation. When compared to conventional drug delivery, nanocarriers drug delivery offers various benefits, such as excellent reliability, bioactivity, improved penetration and retention impact, as well as precise targeting and administering. Upregulation of drug efflux transporters, dysfunctional apoptotic mechanisms, and a hypoxic atmosphere are all elements that lead to cancer treatment sensitivity in humans. It has been possible to target these pathways using nanoparticles and increase the effectiveness of multidrug resistance treatments. As innovative strategies of tumor chemoresistance are uncovered, nanomaterials are being developed to target specific pathways of tumor resilience. Scientists have recently begun investigating the function of nanoparticles in immunotherapy, a field that is becoming increasingly useful in the care of malignancies. Nanoscale therapeutics have been explored in this scientific literature and represent the most current approaches to neurodegenerative illnesses and cancer therapy. In addition, current findings and various biomedical nanomaterials' future promise for tissue regeneration, prospective medication design, and the synthesis of novel delivery approaches have been emphasized.