Poly(ϵ-Caprolactone) Nanospheres Coated on Dental Implants by Integrated Layer-by-Layer Coating Technique
| dc.contributor.author | Patiyananuwat N. | |
| dc.contributor.author | Chartpitak T. | |
| dc.contributor.author | Tancharoen S. | |
| dc.contributor.author | Nasongkla N. | |
| dc.contributor.other | Mahidol University | |
| dc.date.accessioned | 2023-10-19T18:01:18Z | |
| dc.date.available | 2023-10-19T18:01:18Z | |
| dc.date.issued | 2023-01-01 | |
| dc.description.abstract | Dental implant infections are a leading cause of implant failure, causing inflammation and bone loss. To combat such infections, a potential solution is the application of a nano-coating technique that utilizes nanotechnology and a drug delivery system to coat the implant surface. This study aimed to coat dental implants with poly(ϵ-caprolactone) nanospheres (PCL-NPs) loaded with minocycline (MC), an antibacterial agent, using the Layer-by-Layer (LbL) coating technique involving dipping and spraying. The dental implants were coated for 30, 60, 90, and 120 cycles, respectively. The MC/PCL- NPs achieved drug-loading contents of 0.16 ± 0.03, 3.03 ± 0.99, 5.87 ± 0.69, and 6.48 ± 1.68 mg, respectively. The antibacterial study revealed that the release profile of minocycline from the coated dental implants effectively inhibited bacteria growth for a duration of three days. Keywords: Dental implant, nano-coating, nanospheres, poly(ϵ-caprolactone), minocycline, drug delivery system | |
| dc.identifier.citation | Proceedings of the IEEE Conference on Nanotechnology Vol.2023-July (2023) , 484-489 | |
| dc.identifier.doi | 10.1109/NANO58406.2023.10231250 | |
| dc.identifier.eissn | 19449380 | |
| dc.identifier.issn | 19449399 | |
| dc.identifier.scopus | 2-s2.0-85173589680 | |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/123456789/90564 | |
| dc.rights.holder | SCOPUS | |
| dc.subject | Chemical Engineering | |
| dc.title | Poly(ϵ-Caprolactone) Nanospheres Coated on Dental Implants by Integrated Layer-by-Layer Coating Technique | |
| dc.type | Conference Paper | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85173589680&origin=inward | |
| oaire.citation.endPage | 489 | |
| oaire.citation.startPage | 484 | |
| oaire.citation.title | Proceedings of the IEEE Conference on Nanotechnology | |
| oaire.citation.volume | 2023-July | |
| oairecerif.author.affiliation | Mahidol University, Faculty of Dentistry | |
| oairecerif.author.affiliation | Mahidol University |