Enhancing leptospirosis control with nanosensing technology: A critical analysis
Issued Date
2024-01-01
Resource Type
ISSN
01479571
eISSN
18781667
Scopus ID
2-s2.0-85178303013
Journal Title
Comparative Immunology, Microbiology and Infectious Diseases
Volume
104
Rights Holder(s)
SCOPUS
Bibliographic Citation
Comparative Immunology, Microbiology and Infectious Diseases Vol.104 (2024)
Suggested Citation
Suwannin P., Jangpatarapongsa K., Polpanich D., Alhibshi A., Errachid A., Elaissari A. Enhancing leptospirosis control with nanosensing technology: A critical analysis. Comparative Immunology, Microbiology and Infectious Diseases Vol.104 (2024). doi:10.1016/j.cimid.2023.102092 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/91404
Title
Enhancing leptospirosis control with nanosensing technology: A critical analysis
Other Contributor(s)
Abstract
Leptospirosis is a serious health problem in tropical areas; thus, animals shed leptospires in the environment. Humans are accidental hosts infected through exposure to contaminating bacteria in the environment. One health strategy can be applied to protect and eliminate leptospirosis because this cooperates and coordinates activities between doctors, veterinarians, and ecologists. However, conventional methods still have limitations. Therefore, the main challenges of leptospirosis control are the high sensing of detection methods to screen and control the pathogens. Interestingly, nano sensing combined with a leptospirosis detection approach can increase the sensitivity and eliminate some limitations. This article reviews nanomaterial development for an advanced leptospirosis detection method, e.g., latex beads-based agglutination test, magnetic nanoparticles enrichment, and gold-nanoparticles-based immunochromatographic assay. Thus, nanomaterials can be functionalized with biomolecules or sensing molecules utilized in various mechanisms such as biosensors. Over the last decade, many biosensors have been developed for Leptospira spp. pathogen and others. The evolution of biosensors for leptospirosis detection was designed for high efficiency and might be an alternative tool. In addition, the high-sensing fabrications are useful for leptospires screening in very low levels, for example, soil or water from the environment.