Retinal Microvasculature: A Potential Window Into Heart Failure Prevention
Issued Date
2022-11-01
Resource Type
ISSN
22131779
Scopus ID
2-s2.0-85140269487
Pubmed ID
36328644
Journal Title
JACC: Heart Failure
Volume
10
Issue
11
Start Page
785
End Page
791
Rights Holder(s)
SCOPUS
Bibliographic Citation
JACC: Heart Failure Vol.10 No.11 (2022) , 785-791
Suggested Citation
Chaikijurajai T., Ehlers J.P., Tang W.H.W. Retinal Microvasculature: A Potential Window Into Heart Failure Prevention. JACC: Heart Failure Vol.10 No.11 (2022) , 785-791. 791. doi:10.1016/j.jchf.2022.07.004 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/85416
Title
Retinal Microvasculature: A Potential Window Into Heart Failure Prevention
Author(s)
Author's Affiliation
Other Contributor(s)
Abstract
Endothelial dysfunction and microvascular disease have been shown to play an important role in the development and progression of heart failure (HF). Retinal imaging provides a unique opportunity to noninvasively assess vascular structure and function, vessel features, and microcirculation within the retina. Accumulating evidence suggests that retinal vessel caliber, microvascular features, and vascular characteristics extracted from various imaging modalities are associated with alterations in left ventricular structure and function in stage B HF, as well as incident development of symptomatic HF in the general population. Moreover, dynamic retinal vessel analysis has been shown to differentiate HF patients based on their phenotypes. Given the increasing availability of rapid image acquisition devices (eg, nonmydriatic widefield systems and smartphone-based retinal cameras) and the integration of artificial intelligence–based interrogation/assessment techniques, retinal imaging is a promising noninvasive tool, in conjunction with cardiac imaging and biomarkers, to prevent HF and risk stratify those at risk of developing HF. This review focuses on the current evidence on retinal microvasculature changes, and potential clinical relevance and promising utility of retinal imaging in HF.