Establishment of human induced pluripotent stem cell line MUi028-A from normal fetal skin fibroblasts

dc.contributor.authorChumchuen S.
dc.contributor.authorSatirapod C.
dc.contributor.authorTangprasittipap A.
dc.contributor.authorHongeng S.
dc.contributor.otherMahidol University
dc.date.accessioned2023-06-22T10:30:41Z
dc.date.available2023-06-22T10:30:41Z
dc.date.issued2022-04-01
dc.description.abstractMUi028-A human induced pluripotent stem cell (hiPSC) line was generated from normal fetal skin fibroblasts using a non-integrative reprogramming method. Reprogramming factors OCT4, SOX2, KLF4, L-MYC, and LIN28, and TP53 shRNA in three episomal vectors were delivered by electroporation. The MUi028-A cell line had embryonic stem cell characteristics with consistent expression of specific pluripotency markers and the capability of in vitro differentiation into the three germ layers. This iPSC line can be used as a control to study disease mechanisms.
dc.identifier.citationStem Cell Research Vol.60 (2022)
dc.identifier.doi10.1016/j.scr.2022.102675
dc.identifier.eissn18767753
dc.identifier.issn18735061
dc.identifier.pmid35114587
dc.identifier.scopus2-s2.0-85123775729
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/87496
dc.rights.holderSCOPUS
dc.subjectBiochemistry, Genetics and Molecular Biology
dc.titleEstablishment of human induced pluripotent stem cell line MUi028-A from normal fetal skin fibroblasts
dc.typeArticle
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85123775729&origin=inward
oaire.citation.titleStem Cell Research
oaire.citation.volume60
oairecerif.author.affiliationFaculty of Medicine Ramathibodi Hospital, Mahidol University

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