Effect of GuttaClear on Postoperative Pain After Root Canal Retreatment: A Randomized Clinical Trial
Issued Date
2023-01-01
Resource Type
eISSN
25480839
Scopus ID
2-s2.0-85147461195
Pubmed ID
36748447
Journal Title
European endodontic journal
Volume
8
Issue
1
Start Page
55
End Page
64
Rights Holder(s)
SCOPUS
Bibliographic Citation
European endodontic journal Vol.8 No.1 (2023) , 55-64
Suggested Citation
Sirijindamai D., Wichai W., Mitrirattanakul S., Jantarat J. Effect of GuttaClear on Postoperative Pain After Root Canal Retreatment: A Randomized Clinical Trial. European endodontic journal Vol.8 No.1 (2023) , 55-64. 64. doi:10.14744/eej.2022.85047 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/81825
Title
Effect of GuttaClear on Postoperative Pain After Root Canal Retreatment: A Randomized Clinical Trial
Author's Affiliation
Other Contributor(s)
Abstract
OBJECTIVE: The aim of this study was to evaluate postoperative pain after non-surgical root canal retreatment with or without GuttaClear. METHODS: Sixty participants were randomly distributed in this non-inferiority trial into two parallel singleblinded experimental groups (Group1: non-solvent, Group2: solvent). After root canal retreatment, the participants completed questionnaires using direct (numerical rating scales) and indirect (number of analgesics taken) measurements of postoperative pain at immediate, 6, 12, 24, 48, and 72 h post-retreatment. The predisposing postoperative pain factors were recorded and analysed using Generalized Estimating Equations to identify correlated factors (α=0.05). RESULTS: The pain incidence was not significantly different between the groups at any time point. The highest incidence of postoperative pain occurred immediately after retreatment (35%) and then decreased to 15% at 24 h (P<0.05). The number of participants requiring analgesics was 6.67% in the non-solvent group and 9.99% in the solvent group which were similar between the groups. Patients with a history of previous postoperative pain were 21.6-fold more likely to have postoperative pain than those without (P<0.05). CONCLUSION: There was no difference in postoperative pain or analgesics required after root canal retreatment with or without using GuttaClear. This study is registered in ClinicalTrial.gov (NCT04326998). (EEJ-2022-05-069).