Novel vinegar solution for denture-cleansing agent
Issued Date
2023-01-01
Resource Type
ISSN
13434934
eISSN
18804926
Scopus ID
2-s2.0-85151180348
Pubmed ID
36990755
Journal Title
Journal of Oral Science
Volume
65
Issue
2
Start Page
117
End Page
120
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Oral Science Vol.65 No.2 (2023) , 117-120
Suggested Citation
Kaypetch R., Anuwongnukroh N., Dechkunakorn S., Wichai W., Tua-Ngam P., Tantivitayakul P., Shrestha B. Novel vinegar solution for denture-cleansing agent. Journal of Oral Science Vol.65 No.2 (2023) , 117-120. 120. doi:10.2334/josnusd.22-0385 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/81822
Title
Novel vinegar solution for denture-cleansing agent
Author's Affiliation
Other Contributor(s)
Abstract
Purpose: To study the antimicrobial effects of a novel vinegar-based denture cleansing agent on oral Streptococci and Candida species and the inhibitory effects on pre-formed bacterial and Candida biofilms on denture base. Methods: The microorganisms used in this study were Streptococcus mutans (S. mutans), Streptococcus sobrinus (S. sobrinus), Streptococcus sanguinis (S. sanguinis), Candida albicans (C. albicans), and Candida glabrata (C. glabrata). The antimicrobial activity of novel vinegar solution was evaluated by time kill assay and biofilm grown on denture base. Results: Time kill assay showed that vinegar exhibited the highest anti-bacterial effect on S. sobrinus, S. sanguinis, and S. mutans after 15 min of treatment. A 99.9% reduction in C. glabrata and C. albicans required more than 4 and 6 h of treatment, respectively. Vinegar significantly inhibited streptococcal biofilm, with an approximately 6 log-reduction at 30 min of treatment. The results demonstrated that viable Candida cells in biofilm reduced in excess of 6-log CFU/mL after 3 h treatment with vinegar. More-over, the vinegar-based denture cleanser inhibited bacterial and Candida biofilm formation compared to the control group without treatment with statistical significance. Conclusion: A novel vinegar-based denture cleansing agent showed mod-erate antibacterial properties, but required a slightly longer immersion time to attain anticandidal effects compared to Polident and 0.2% CHX.