Clinical characteristics and outcomes of ocular allergy in Thai children
Issued Date
2022-01-01
Resource Type
ISSN
0125877X
eISSN
22288694
Scopus ID
2-s2.0-85147045727
Pubmed ID
32061246
Journal Title
Asian Pacific Journal of Allergy and Immunology
Volume
40
Issue
4
Start Page
407
End Page
413
Rights Holder(s)
SCOPUS
Bibliographic Citation
Asian Pacific Journal of Allergy and Immunology Vol.40 No.4 (2022) , 407-413
Suggested Citation
Jongvanitpak R., Vichyanond P., Jirapongsananuruk O., Visitsunthorn N., Pacharn P. Clinical characteristics and outcomes of ocular allergy in Thai children. Asian Pacific Journal of Allergy and Immunology Vol.40 No.4 (2022) , 407-413. 413. doi:10.12932/ap-160519-0564 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/85039
Title
Clinical characteristics and outcomes of ocular allergy in Thai children
Author's Affiliation
Other Contributor(s)
Abstract
Background: Allergic conjunctivitis (AC) is the most common ocular condition in allergic children. In tropical countries, the study about the clinical features and outcome of treatment is very limited. Objective: To review clinical characteristics and outcomes of treatment in children with ocular allergy. Methods: Children with history of AC were classified to seasonal allergic conjunctivitis (SAC), perennial allergic conjunctivitis (PAC), vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC). The clinical history and outcome of treatment were recorded. Results: One hundred and sixty-four children were recruited. PAC was the most common type (61.6%), followed by SAC (21.3%), VKC (12.2%), and AKC (4.9%). Male preponderance was found in all groups. Mean age of onset was 6.8 ± 2.8 years. Allergic rhinitis was the most common co-morbidity (97.6%). The common sensitized allergen is house-dust mites (86.1%). Standard treatments in all groups were natural tear and topical olopatadine. Add-on medications were usually needed in severe types of AC (VKC, AKC). History of topical corticosteroid use was 68.8% and 12.5% in VKC and AKC, respectively. All of them can discontinue topical corticosteroid when topical tacrolimus was applied. The overall remission was found 35% in VKC group and 63% in AKC group. The median duration of treatment was 20.5 months in VKC group and 11 months in AKC group. Conclusion: Most Thai children with AC sensitized to house-dust mites. In severe forms of AC, most patients needed add-on medication. The use of topical calcineurin inhibitor as an add-on therapy can decrease the use of topical corticosteroid.