Gut microbiome modulation and gastrointestinal digestibility in vitro of polysaccharide-enriched extracts and seaweeds from Ulva rigida and Gracilaria fisheri
Issued Date
2022-09-01
Resource Type
ISSN
17564646
Scopus ID
2-s2.0-85135145598
Journal Title
Journal of Functional Foods
Volume
96
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Functional Foods Vol.96 (2022)
Suggested Citation
Charoensiddhi S., Conlon M., Methacanon P., Thayanukul P., Hongsprabhas P., Zhang W. Gut microbiome modulation and gastrointestinal digestibility in vitro of polysaccharide-enriched extracts and seaweeds from Ulva rigida and Gracilaria fisheri. Journal of Functional Foods Vol.96 (2022). doi:10.1016/j.jff.2022.105204 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/83159
Title
Gut microbiome modulation and gastrointestinal digestibility in vitro of polysaccharide-enriched extracts and seaweeds from Ulva rigida and Gracilaria fisheri
Other Contributor(s)
Abstract
This study explored the gut health potential of the green seaweed Ulva rigida (SW-U) and the red seaweed Gracilaria fisheri (SW-G), as well as polysaccharide-enriched extracts (PF-U and PF-G, respectively). The polysaccharide-enriched extracts were not digestible by small intestinal enzymes, but the morphology of samples was changed. After 24 h in vitro fermentation, seaweeds and polysaccharide-enriched extracts significantly increased (p < 0.05) production of total short-chain fatty acids (SCFAs) (29.4–35.4 µmoL/mL) compared to the control (17.9 µmoL/mL). The G. fisheri showed more potential for improving gut health than U. rigida. Particularly, PF-G induced butyric acid production comparable to that of inulin control (5.4 and 6.9 µmoL/mL) and the highest production when compared with other substrates (1.8–3.3 µmoL/mL). While SW-G stimulated the growth of beneficial bacteria, including Roseburia and Faecalibacterium. These findings further demonstrate that seaweeds and their derived polysaccharides have the potential to be used as dietary supplements with gut health benefits.